[前列环素-血栓素系统与不同年龄缺血性心脏病患者血小板的功能特性]
[The prostacyclin-thromboxane system and the functional properties of the thrombocytes in patients of different ages with ischemic heart disease].
作者信息
Ermakovich I I, Ladnyĭ A I, Volkov V I, Tseluĭko V I
出版信息
Vrach Delo. 1990 Sep(9):25-8.
A study is presented of the reactions of prostacyclin-thromboxane system and functions of thrombocytes to physical loads inducing myocardial ischemia in patients with ischemic heart disease of different age groups. Examined were 62 patients with stable stenocardia of the II and III functional classes. Age of the patients: from 44 to 60 years. It was found that the elderly showed deterioration of the prostacyclin-thromboxane imbalance and a reduction of the sensitivity of thrombocytes to prostacyclin. The should be considered in instituting prolonged drug treatment.
本文介绍了一项关于不同年龄组缺血性心脏病患者在诱发心肌缺血的体力负荷下前列环素 - 血栓素系统反应及血小板功能的研究。研究对象为62例II级和III级功能稳定型心绞痛患者。患者年龄在44至60岁之间。研究发现，老年患者前列环素 - 血栓素失衡加剧，血小板对前列环素的敏感性降低。在制定长期药物治疗方案时应考虑到这一点。
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