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与在伊拉克或阿富汗服役相关的创伤后应激障碍:协调不同研究之间的患病率差异

Posttraumatic stress disorder associated with combat service in Iraq or Afghanistan: reconciling prevalence differences between studies.

作者信息

Kok Brian C, Herrell Richard K, Thomas Jeffrey L, Hoge Charles W

机构信息

Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.

出版信息

J Nerv Ment Dis. 2012 May;200(5):444-50. doi: 10.1097/NMD.0b013e3182532312.

DOI:10.1097/NMD.0b013e3182532312
PMID:22551799
Abstract

Studies of posttraumatic stress disorder (PTSD) prevalence associated with deployment to Iraq or Afghanistan report wide variability, making interpretation and projection for research and public health purposes difficult. This article placed this literature within a military context. Studies were categorized according to deployment time-frame, screening case definition, and study group (operational infantry units exposed to direct combat versus population samples with a high proportion of support personnel). Precision weighted averages were calculated using a fixed-effects meta-analysis. Using a specific case definition, the weighted postdeployment PTSD prevalence was 5.5% (95% CI, 5.4-5.6) in population samples and 13.2% (12.8-13.7) in operational infantry units. Both population-level and unit-specific studies provided valuable and unique information for public health purposes; understanding the military context is essential for interpreting prevalence studies.

摘要

关于与部署到伊拉克或阿富汗相关的创伤后应激障碍(PTSD)患病率的研究报告显示出很大的差异,这使得出于研究和公共卫生目的进行解释和预测变得困难。本文将这些文献置于军事背景中。研究根据部署时间框架、筛查病例定义和研究组(暴露于直接战斗的作战步兵部队与支持人员比例高的人群样本)进行分类。使用固定效应荟萃分析计算精确加权平均值。采用特定的病例定义,人群样本中部署后PTSD的加权患病率为5.5%(95%CI,5.4 - 5.6),作战步兵部队中为13.2%(12.8 - 13.7)。人群层面和特定部队的研究都为公共卫生目的提供了有价值且独特的信息;了解军事背景对于解释患病率研究至关重要。

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