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本文引用的文献

1
Open-source genomic analysis of Shiga-toxin-producing E. coli O104:H4.产志贺毒素大肠杆菌 O104:H4 的开源基因组分析。
N Engl J Med. 2011 Aug 25;365(8):718-24. doi: 10.1056/NEJMoa1107643. Epub 2011 Jul 27.
2
Molecular characterization and phylogenetic analysis of quinolone resistance-determining regions (QRDRs) of gyrA, gyrB, parC and parE gene loci in viridans group streptococci isolated from adult patients with cystic fibrosis.从囊性纤维化成年患者中分离出的草绿色链球菌中 gyrA、gyrB、parC 和 parE 基因座喹诺酮耐药决定区 (QRDRs) 的分子特征和系统发育分析。
J Antimicrob Chemother. 2011 Mar;66(3):476-86. doi: 10.1093/jac/dkq485. Epub 2010 Dec 29.
3
Cephalosporin and fluoroquinolone combinations are highly associated with CTX-M β-lactamase-producing Escherichia coli: a case-control study in a French teaching hospital.头孢菌素和氟喹诺酮类药物联合使用与产 CTX-M 型β-内酰胺酶大肠埃希菌高度相关：法国教学医院的一项病例对照研究。
Clin Microbiol Infect. 2011 Nov;17(11):1746-51. doi: 10.1111/j.1469-0691.2010.03349.x. Epub 2011 Apr 12.
4
An overview of atypical enteropathogenic Escherichia coli.非典型肠道致病性大肠杆菌概述
FEMS Microbiol Lett. 2009 Aug;297(2):137-49. doi: 10.1111/j.1574-6968.2009.01664.x. Epub 2009 May 27.
5
Prevalence of quinolone-resistant urinary tract infections in Comanche County Memorial Hospital.科曼奇县纪念医院喹诺酮耐药性尿路感染的患病率
J Okla State Med Assoc. 2008 Sep;101(9):210-2.
6
Attaching and effacing Escherichia coli isolates from Danish children: clinical significance and microbiological characteristics.丹麦儿童中黏附性侵袭性大肠杆菌分离株：临床意义及微生物学特征
Clin Microbiol Infect. 2007 Sep;13(9):863-72. doi: 10.1111/j.1469-0691.2007.01773.x.
7
Multiplex PCR for detection of plasmid-mediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates.用于检测产超广谱β-内酰胺酶肠杆菌分离株中质粒介导喹诺酮耐药qnr基因的多重聚合酶链反应
J Antimicrob Chemother. 2007 Aug;60(2):394-7. doi: 10.1093/jac/dkm204. Epub 2007 Jun 8.
8
Resistance in gram-negative bacteria: Enterobacteriaceae.革兰氏阴性菌中的耐药性：肠杆菌科细菌。
Am J Infect Control. 2006 Jun;34(5 Suppl 1):S20-8; discussion S64-73. doi: 10.1016/j.ajic.2006.05.238.
9
Molecular epidemiology of ceftiofur-resistant Escherichia coli isolates from dairy calves.来自奶牛犊的头孢噻呋耐药性大肠杆菌分离株的分子流行病学
Appl Environ Microbiol. 2006 Jun;72(6):3940-8. doi: 10.1128/AEM.02770-05.
10
Evaluation of multiplex PCRs for diagnosis of infection with diarrheagenic Escherichia coli and Shigella spp.用于诊断致泻性大肠杆菌和志贺氏菌属感染的多重聚合酶链反应评估
J Clin Microbiol. 2004 Dec;42(12):5849-53. doi: 10.1128/JCM.42.12.5849-5853.2004.

中国食物中毒暴发中由产extended-spectrum-beta-lactamase 表型的喹诺酮耐药性大肠杆菌 O127a:K63 血清型引起的。

Quinolone-resistant Escherichia coli O127a:K63 serotype with an extended-spectrum-beta-lactamase phenotype from a food poisoning outbreak in China.

机构信息

Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.

出版信息

J Clin Microbiol. 2012 Jul;50(7):2450-1. doi: 10.1128/JCM.00276-12. Epub 2012 May 2.

DOI:10.1128/JCM.00276-12
PMID:22553233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3405572/
Abstract

We report an atypical enteropathogenic Escherichia coli O127a:K63 strain with resistance to quinolones and extended-spectrum cephalosporins isolated from a 2010 food poisoning outbreak involving 112 adults in China. Two resistance genes [bla(CTX-M-15), aac(6')-Ib-c] and five mutations (two in gyrA, two in parC, one in parE) coexisted in this enteropathogenic E. coli strain.

摘要

我们报告了一株来自中国 2010 年一起涉及 112 名成年人的食源性疾病暴发的非典型肠致病性大肠杆菌 O127a:K63 菌株，该菌株对喹诺酮类和头孢菌素类抗生素均具有耐药性。该肠致病性大肠杆菌菌株中同时存在两种耐药基因[bla(CTX-M-15)，aac(6')-Ib-c]和五种突变（gyrA 中的两种、parC 中的两种、parE 中的一种）。