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Application of ultrasound contrast in identification and diagnosis of ocular spaceoccupying lesions.超声造影在眼部占位性病变诊断与鉴别诊断中的应用
Int J Ophthalmol. 2011;4(4):337-42. doi: 10.3980/j.issn.2222-3959.2011.04.02. Epub 2011 Aug 18.
2
Application of ultrasound microbubble contrast technology in ophthalmic targeted therapy: literature analysis.超声微泡造影技术在眼科靶向治疗中的应用:文献分析
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Italian Society of Cardiovascular Echography (SIEC) Consensus Conference on the state of the art of contrast echocardiography.意大利心血管超声学会(SIEC)关于超声造影技术现状的共识会议
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Assessment of microcirculation by contrast-enhanced ultrasound: a new approach in vascular medicine.超声造影评估微循环:血管医学的一种新方法。
Swiss Med Wkly. 2015 Jan 14;145:w14047. doi: 10.4414/smw.2015.14047. eCollection 2015.
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Contrast-enhanced ultrasound in diagnosis and characterization of focal hepatic lesions.超声造影在肝脏局灶性病变的诊断与特征分析中的应用
World J Radiol. 2010 Dec 28;2(12):455-62. doi: 10.4329/wjr.v2.i12.455.
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Microcirculation and perfusion with contrast enhanced ultrasound (CEUS) in Crohn's disease: first results with linear contrast harmonic imaging (CHI).克罗恩病中使用超声造影(CEUS)的微循环与灌注:线性对比谐波成像(CHI)的初步结果
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[Contrast-enhanced Ultrasound in Diagnostic Imaging of Muscle Injuries: Perfusion Imaging in the Early Arterial Phase].[超声造影在肌肉损伤诊断成像中的应用:动脉早期灌注成像]
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New real-time image fusion technique for characterization of tumor vascularisation and tumor perfusion of liver tumors with contrast-enhanced ultrasound, spiral CT or MRI: first results.新型实时图像融合技术在超声造影、螺旋 CT 或 MRI 下对肝脏肿瘤血管生成和肿瘤灌注的特征描述:初步结果。
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[New application of ultrasound imaging using contrast agent].[使用造影剂的超声成像新应用]
Nihon Rinsho. 1998 Apr;56(4):843-7.

本文引用的文献

1
Echographic examination with new generation contrast agent of choroidal malignant melanomas.使用新一代造影剂对脉络膜恶性黑色素瘤进行超声检查。
Acta Ophthalmol Scand. 2005 Jun;83(3):347-54. doi: 10.1111/j.1600-0420.2005.00428.x.
2
High-frequency contrast harmonic imaging of ophthalmic tumor perfusion.眼科肿瘤灌注的高频对比谐波成像
AJR Am J Roentgenol. 2005 Feb;184(2):574-8. doi: 10.2214/ajr.184.2.01840574.
3
Echoscintigraphy: a new imaging modality for the reduction of color blooming and acoustic shadowing in contrast sonography.超声闪烁造影:一种减少超声造影中彩色外溢和声学阴影的新型成像方式。
Ultrasound Med Biol. 2003 Jul;29(7):985-91. doi: 10.1016/s0301-5629(03)00890-1.
4
Significance of angiogenesis and microvascular invasion in renal cell carcinoma.血管生成和微血管侵犯在肾细胞癌中的意义
Pathol Oncol Res. 2002;8(2):129-32. doi: 10.1007/BF03033722.
5
Multi-centre clinical study evaluating the efficacy of SonoVue (BR1), a new ultrasound contrast agent in Doppler investigation of focal hepatic lesions.一项多中心临床研究,评估新型超声造影剂声诺维(BR1)在局灶性肝病变多普勒检查中的疗效。
Eur J Radiol. 2002 Mar;41(3):200-6. doi: 10.1016/s0720-048x(01)00457-0.
6
Contrast-enhanced color Doppler sonography of uveal melanomas.葡萄膜黑色素瘤的对比增强彩色多普勒超声检查
J Clin Ultrasound. 2001 May;29(4):205-11. doi: 10.1002/jcu.1021.
7
Clinical safety of SonoVue, a new contrast agent for ultrasound imaging, in healthy volunteers and in patients with chronic obstructive pulmonary disease.新型超声成像造影剂声诺维在健康志愿者和慢性阻塞性肺疾病患者中的临床安全性。
Invest Radiol. 2001 Feb;36(2):104-9. doi: 10.1097/00004424-200102000-00006.
8
Human pharmacokinetics and safety evaluation of SonoVue, a new contrast agent for ultrasound imaging.新型超声造影剂声诺维的人体药代动力学及安全性评估。
Invest Radiol. 2000 Jan;35(1):80-5. doi: 10.1097/00004424-200001000-00009.
9
[Doppler color ultrasonography with contrast media in the study of eye and orbit neoplasms].[超声造影剂在眼部及眼眶肿瘤研究中的多普勒彩色超声检查]
Radiol Med. 1997 Apr;93(4):367-73.

超声造影在眼部占位性病变诊断与鉴别诊断中的应用

Application of ultrasound contrast in identification and diagnosis of ocular spaceoccupying lesions.

作者信息

Yuan Jia-Ying, Zhang Jian-Hua, Tang Chong, Zhao Jing-Zhi, Pang Chao, Ren Xin-Chun, Zhu Hong, Zhang Yun-Tao

机构信息

Department of Ultrasonography, Hospital of Military Area of He'nan Zhengzhou 450003, He'nan Province, China.

出版信息

Int J Ophthalmol. 2011;4(4):337-42. doi: 10.3980/j.issn.2222-3959.2011.04.02. Epub 2011 Aug 18.

DOI:10.3980/j.issn.2222-3959.2011.04.02
PMID:22553676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3340855/
Abstract

AIM

To analyze the application significance of ultrasound contrast agent in identification and diagnosis of ocular spaceoccupying lesions, and mainly analyze its advantages and problems.

METHODS

Thirty-two representative literatures about the application of ultrasound contrast agent in diagnosis of spaceoccupying lesions at home and abroad were collected after focused on sorting the literature reporting the application of ultrasound contrast diagnostic technology in the diagnosis and identification of ocular spaceoccupying lesions in recent years. Its advantages and problems were retrospectively analyzed, and reasonable assessment on existing problems was made and possible solutions to the problems were proposed.

RESULTS

As a new imaging diagnostic technique, the contrast-enhanced ultrasound, which can enhance the display of tumor microcirculation vessels and improve the tumor's ultrasound diagnostic capability, was analyzed. Through sorting and comprehensively analyzing the collected literatures, the positive rate of ocular spaceoccupying lesion diagnosis could be significantly improved with ultrasound contrast technology. Thus, the vascular perfusion in normal tissues and lesions was reflected objectively. According to the lesion's perfusion characteristics of the contrast agent plus with the performance features of two-dimensional ultrasound, the ocular spaceoccupying lesions can be accurately diagnosed, and this could provide clinicians with reliable research basis in this field.

CONCLUSION

Ultrasound contrast examination is a new testing method, and ultrasound contrast agent can significantly enhance the ultrasonic detection signal, clearly show the blood perfusion in vessels and tissues, increase the image contrast resolution, and improve the lesion's detection capability in the microcirculation perfusion level, especially its important value in the diagnosis of ocular tumor.

摘要

目的

分析超声造影剂在眼部占位性病变鉴别诊断中的应用意义,重点分析其优势及存在的问题。

方法

聚焦近年来报道超声诊断技术在眼部占位性病变诊断及鉴别诊断中应用的文献,收集国内外32篇关于超声造影剂在占位性病变诊断中应用的代表性文献。对其优势及问题进行回顾性分析,对存在的问题作出合理评估并提出可能的解决办法。

结果

分析了超声造影这一可增强肿瘤微循环血管显示、提高肿瘤超声诊断能力的新型成像诊断技术。通过对收集的文献进行整理和综合分析,超声造影技术可显著提高眼部占位性病变的诊断阳性率,客观反映正常组织及病变内的血管灌注情况。根据造影剂的病变灌注特征并结合二维超声的表现特点,可准确诊断眼部占位性病变,为临床医生在该领域提供可靠的研究依据。

结论

超声造影检查是一种新型检查方法,超声造影剂可显著增强超声检测信号,清晰显示血管及组织内的血流灌注情况,提高图像对比分辨率,提升在微循环灌注水平对病变的检测能力,尤其在眼部肿瘤诊断中具有重要价值。