Department of Pediatric Surgery, Maulana Azad Medical College, Bahadur Shah Zafar Marg, New Delhi, 110002, India.
Indian J Pediatr. 2012 Jun;79(6):776-86. doi: 10.1007/s12098-012-0747-3. Epub 2012 May 4.
The management of Wilms' tumor emerging of the outstanding clinical trials undertaken in the developed world in the last four decades has led to excellent longterm outcomes. The scenario in developing country like India is different; late presentation with massive tumors and advanced stage, lacunae in staging, nonavailability of pediatric medical oncologists and poor follow-ups are common. A comprehensive summary of available therapeutic modalities is provided here along with clear roadmaps of management of Wilms' tumor as per Société Internationale d'Oncologie Pédiatrique (SIOP) and National Wilms' Tumor Study Group/Children's Oncology Group (NWTSG/COG) protocols in simple tabulated form.
在过去四十年中,发达国家开展的杰出临床试验对威尔姆斯瘤的治疗进行了管理,从而取得了极好的长期效果。在印度等发展中国家,情况则有所不同;患者就诊时肿瘤巨大且已处于晚期,分期存在空白,缺乏儿童肿瘤专家,且随访情况较差。本文提供了现有的治疗方法的综合总结,并以简洁的表格形式提供了根据国际小儿肿瘤学会(SIOP)和国家威尔姆斯瘤研究组/儿童肿瘤组(NWTSG/COG)方案进行的威尔姆斯瘤治疗管理的明确路线图。