[Early results of the treatment of patients with recurrences of pulmonary tuberculosis].

Efficacy of treatment of 106 patients with destructive forms of recurring pulmonary tuberculosis is analysed. Treatment was conducted in comparable groups on 2 chemotherapeutic regimens. With regimen 1 consisting of a 4-drug combination, cavity closure was evident in 72.2%, while with regimen 2 including 3 drugs, cavities were closed in 42.3% of the cases. Cavity decay healing and bacteriostasis rates were higher for regimen 1 as compared to regimen 2, though the incidence of bacteriostasis was the same with both chemotherapeutic regimens, i.e. in 93.6% and in 92.8% with regimen 1 and 2, respectively. The incidence of side effects was practically unchanged in terms of the given chemotherapeutic regimen. A 4-drug combination should be chosen for the management of patients with destructive recurring pulmonary tuberculosis.