Department of Dermatology, Churchill Hospital, Old Road, Oxford OX3 7LJ, UK.
Immunol Allergy Clin North Am. 2012 May;32(2):245-53, vi. doi: 10.1016/j.iac.2012.04.004. Epub 2012 Apr 17.
Linear IgA disease is one of the rarer subepidermal blistering diseases. Linear IgA disease is a chronic, acquired, autoimmune blistering disease that is characterized by subepidermal blistering and linear deposition of IgA basement membrane antibodies. The disease affects both children and adults and, although there are some differences in their clinical presentations, there is considerable overlap with shared immunopathology and immunogenetics.
线性 IgA 病是一种较为罕见的表皮下大疱性皮肤病。线性 IgA 病是一种慢性、获得性、自身免疫性大疱病，其特征是表皮下大疱形成和 IgA 基底膜抗体线性沉积。这种疾病可影响儿童和成人，尽管其临床表现存在一些差异，但它们具有共同的免疫病理学和免疫遗传学，存在很大的重叠。
