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连枷胸肋骨骨折固定:有何益处?

Rib fracture fixation for flail chest: what is the benefit?

机构信息

Section of Burns/Trauma/Critical Care, Department of Surgery, University of Utah, Salt Lake City, UT 84132, USA.

出版信息

J Am Coll Surg. 2012 Aug;215(2):201-5. doi: 10.1016/j.jamcollsurg.2012.02.023. Epub 2012 May 4.

Abstract

BACKGROUND

Recently, rib fracture fixation for flail chest has been used increasingly at both academic and nonacademic trauma centers. Although a few small non-US studies have demonstrated a clinical benefit, it is unclear whether this benefit outweighs the added expense and potential perioperative complications related to the procedure. We therefore sought to determine if open reduction and internal fixation of ribs for flail chest (ORIF-FC) represents a cost-effective means for managing these patients.

STUDY DESIGN

A Markov transition state analysis was performed modeling the outcomes of the standard of care or ORIF-FC for flail chest. The incidences of ventilator-associated pneumonia, tracheostomy, sepsis, prolonged ventilation, deep vein thrombosis, pulmonary embolism, wound infection, and postoperative hemorrhage were obtained based on literature review. Medicare 2010 reimbursement costs were used for diagnoses and procedures. A quality of life improvement factor ranging from 0 to 15% improvement was used to estimate the improvement in pain and functional outcomes related to ORIF-FC. The most cost-effective treatment was then determined, ranging the incidences of ventilator-associated pneumonia and quality of life improvement factor.

RESULTS

Cost effectiveness was $15,269 for ORIF-FC compared with $16,810 for standard of care. Even when the quality of life improvement factor was set to 0%, ORIF-FC remained the most cost-effective strategy. Similarly, ORIF-FC remained the most cost-effective strategy by $8,400 when the incidence of ventilator-associated pneumonia after ORIF was as high as 22%.

CONCLUSIONS

Despite the additional cost of surgery, rib fracture fixation dominates the standard of care and should be considered in the management of appropriate flail chest patients.

摘要

背景

最近,在学术和非学术创伤中心,都越来越多地使用肋骨骨折固定术来治疗连枷胸。尽管少数几项非美国的小型研究显示出了临床益处,但尚不清楚这种益处是否超过了与该手术相关的额外费用和潜在围手术期并发症。因此,我们试图确定开放性复位内固定肋骨(ORIF-FC)是否是治疗这些患者的一种具有成本效益的方法。

研究设计

采用 Markov 转移状态分析,对连枷胸的标准治疗或 ORIF-FC 的结果进行建模。根据文献综述,获得呼吸机相关性肺炎、气管切开术、败血症、通气时间延长、深静脉血栓形成、肺栓塞、伤口感染和术后出血的发生率。使用 Medicare 2010 报销费用来计算诊断和手术的费用。使用 0%至 15%的生活质量改善因素来估计与 ORIF-FC 相关的疼痛和功能结局的改善。然后根据呼吸机相关性肺炎的发生率和生活质量改善因素来确定最具成本效益的治疗方法。

结果

与标准治疗相比,ORIF-FC 的成本效益为 15269 美元,而标准治疗为 16810 美元。即使将生活质量改善因素设定为 0%,ORIF-FC 仍然是最具成本效益的策略。同样,当 ORIF 后呼吸机相关性肺炎的发生率高达 22%时,ORIF-FC 仍然通过 8400 美元成为最具成本效益的策略。

结论

尽管手术费用增加,但肋骨骨折固定术占据主导地位,应考虑将其用于治疗合适的连枷胸患者。

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