Kocher Gregor J, Sharafi Siamak, Azenha Luis Filipe, Schmid Ralph A
Division of General Thoracic Surgery, University Hospital Bern/Inselspital, Bern, Switzerland.
Center for Communicable Diseases Control, Ministry of Health and Medical Education, Tehran, Iran
Eur J Cardiothorac Surg. 2017 Apr 1;51(4):696-701. doi: 10.1093/ejcts/ezw365.
Traumatic flail chest is a potentially life threatening injury, often associated with prolonged invasive mechanical ventilation and intensive care unit stay. This study evaluates the usefulness and cost-effectiveness of surgical rib stabilization in patients with flail chest resulting in ventilator dependent respiratory insufficiency.
A retrospective study on a consecutive series of patients with flail chest with the need for mechanical ventilation was performed. Effectiveness of rib fixation was evaluated in terms of predictors for prolonged ventilation, cost-effectiveness and outcome.
A total of 61 patients underwent flail chest stabilization using a locked titanium plate fixation system between July 2010 and December 2015 at our institution. 62% ( n = 38) of patients could be weaned from the ventilator within the first 72 h after surgery. Multiple linear regression analysis revealed that closed head injury, bilateral flail chest, number of stabilized ribs and severity of lung contusion were the main independent predictors for prolonged mechanical ventilation (Odds ratio (OR) 6.88; 3.25; 1.52 and 1.42) and tracheostomy (OR 9.17; 2.2; 1.76 and 0.84 ), respectively. Furthermore cost analysis showed that already a two day reduction in ICU stay could outweigh the cost of surgical rib fixation.
Operative rib fixation has the potential to reduce ventilator days and ICU stay and subsequently hospital costs in selected patients with severe traumatic flail chest requiring mechanical ventilation. Especially associated closed head injury can adversely affect mechanical ventilation time. Furthermore the subgroups of patients sustaining a fall from a height and those with flail chest after cardiopulmonary re-animation seem to profit only marginally from surgical rib fixation.
创伤性连枷胸是一种可能危及生命的损伤,常与长时间有创机械通气及入住重症监护病房相关。本研究评估手术肋骨固定术对因连枷胸导致呼吸机依赖型呼吸功能不全患者的有效性及成本效益。
对一系列连续的需要机械通气的连枷胸患者进行回顾性研究。从延长通气的预测因素、成本效益及预后方面评估肋骨固定的有效性。
2010年7月至2015年12月期间,我院共有61例患者采用锁定钛板固定系统进行连枷胸固定术。62%(n = 38)的患者在术后72小时内可脱机。多元线性回归分析显示,闭合性颅脑损伤、双侧连枷胸、固定肋骨数量及肺挫伤严重程度分别是延长机械通气(比值比(OR)6.88;3.25;1.52和1.42)及气管切开(OR 9.17;2.2;1.76和0.84)的主要独立预测因素。此外,成本分析表明,即使ICU住院时间仅缩短两天,也可能超过手术肋骨固定的成本。
对于部分因严重创伤性连枷胸需要机械通气的患者,手术肋骨固定术有可能减少呼吸机使用天数及ICU住院时间,进而降低住院费用。特别是合并的闭合性颅脑损伤会对机械通气时间产生不利影响。此外,高处坠落所致连枷胸患者及心肺复苏后连枷胸患者似乎从手术肋骨固定术中获益甚微。