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手术时间对严重胸部创伤的重伤患者肋骨骨折手术固定后结局的影响——德国创伤登记处的配对分析

Impact of Time of Surgery on the Outcome after Surgical Stabilization of Rib Fractures in Severely Injured Patients with Severe Chest Trauma-A Matched-Pairs Analysis of the German Trauma Registry.

作者信息

Becker L, Schulz-Drost S, Spering C, Franke A, Dudda M, Kamp O, Lefering R, Matthes G, Bieler D

机构信息

Department of Trauma Surgery, Hand and Reconstructive Surgery, University Hospital Essen, Essen, Germany.

Department of Trauma Surgery, Helios Hospital Schwerin, Schwerin, Germany.

出版信息

Front Surg. 2022 May 11;9:852097. doi: 10.3389/fsurg.2022.852097. eCollection 2022.

Abstract

PURPOSE

In severely injured patients with multiple rib fractures, the beneficial effect of surgical stabilization is still unknown. The existing literature shows divergent results, and the indication and especially the right timing of an operation are the subject of a broad discussion. The aim of this study was to determine the influence of the time point of surgical stabilization of rib fractures (SSRF) on the outcome in a multicenter database with special regard to the duration of ventilation, intensive care, and overall hospital stay.

METHODS

Data from the TraumaRegister DGU collected between 2010 and 2019 were used to evaluate patients above 16 years of age with severe rib fractures [Abbreviated Injury Score (AIS)  ≥ 3] who received an SSRF in a matched-pairs analysis. In this matched-pairs analysis, we compared the effects of an early SSRF within 48 h after initial trauma vs. late SSRF 3-10 days after trauma.

RESULTS

After the selection process, we were able to find 142 matched pairs for further evaluation. Early SSRF was associated with a significantly shorter length of stay in the intensive care unit (16.2 days vs. 12.7 days,  = 0.020), and the overall hospital stay (28.5 days vs. 23.4 days,  = 0.005) was significantly longer in the group with late SSRF. Concerning the days on mechanical ventilation, we were able to demonstrate a trend for an approximately 1.5 day shorter ventilation time for patients after early SSRF, although this difference was not statistically significant ( = 0.226).

CONCLUSIONS

We were able to determine the significant beneficial effects of early SSRF resulting in a shorter intensive care unit stay and a shorter length of stay in hospital and additionally a trend to a shorter time on mechanical ventilation.

摘要

目的

在严重多发肋骨骨折患者中,手术固定的有益效果仍不明确。现有文献结果不一,手术指征尤其是合适的手术时机是广泛讨论的主题。本研究的目的是在一个多中心数据库中确定肋骨骨折手术固定(SSRF)时间点对结局的影响,特别关注通气时间、重症监护时间和总住院时间。

方法

使用2010年至2019年期间从创伤注册数据库DGU收集的数据,对16岁以上严重肋骨骨折[简明损伤评分(AIS)≥3]且接受SSRF的患者进行配对分析。在该配对分析中,我们比较了初始创伤后48小时内早期SSRF与创伤后3 - 10天晚期SSRF的效果。

结果

经过筛选过程,我们能够找到142对匹配病例进行进一步评估。早期SSRF与重症监护病房住院时间显著缩短相关(16.2天对12.7天,P = 0.020),晚期SSRF组的总住院时间显著更长(28.5天对23.4天,P = 0.005)。关于机械通气天数,我们能够证明早期SSRF后患者的通气时间有缩短约1.5天的趋势,尽管这种差异无统计学意义(P = 0.226)。

结论

我们能够确定早期SSRF具有显著的有益效果,可缩短重症监护病房住院时间和住院时间,此外还有机械通气时间缩短的趋势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eca6/9130625/c0219a79a14f/fsurg-09-852097-g001.jpg

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