International Center for Biotechnology, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
J Biosci Bioeng. 2012 Jul;114(1):56-8. doi: 10.1016/j.jbiosc.2012.02.027. Epub 2012 May 5.
With the genetically modified Kitasatospora setae NBRC 14216(T) strain, a new β-carboline alkaloid, kitasetaline (1), was produced on solid medium. The structure was elucidated on the basis of physicochemical evidence. This is the first report of this type of alkaloid found in the genus Kitasatospora.
利用基因改良的链霉菌 NBRC 14216(T)菌株,在固体培养基上产生了一种新的β-咔啉生物碱——放线紫红素(1)。根据物理化学证据确定了其结构。这是首次在链霉菌属中发现此类生物碱。