Solooki Saeed, Vosoughi Amir Reza, Masoomi Vahid
Department of Orthopedic Surgery, Research Center for Bone and Joint Diseases, Chamran Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Indian J Med Paediatr Oncol. 2011 Oct;32(4):187-91. doi: 10.4103/0971-5851.95138.
Musculoskeletal tumors are rare, but their descriptive data in any region are important to reduce mortality rate and improve their management.
Retrospectively, 426 pathologic reports from 1997 to 2008 were reviewed in Shiraz University Orthopedic Hospitals which are the main referral centers for musculoskeletal tumors in south of Iran. We collected and analyzed data on age, gender, anatomical site, and histopathologic types of musculoskeletal tumors.
Of the 426 cases, 60.1% were men and 39.9% were women. The commonest malignant bone tumors were osteosarcoma (89; 50.6%), metastasis (30; 17.0%), Ewing's sarcoma (28; 15.9%), and chondrosarcoma (14; 8.0%). The most frequent benign bone tumors were osteochondroma (136; 63.9%), enchondroma (23; 10.8%), giant cell tumor (21; 9.9%), and osteoid osteoma (14; 6.6%). The femur was the most commonly involved site in musculoskeletal tumors. It was followed by the tibia in benign tumors and the humerus in malignant ones. Metastasis (28; 32.6%), soft tissue tumors (18; 20.9%), osteochondroma (10; 11.6%), and osteosarcoma (9; 10.5%) were the most diagnosed bone lesions in patients older than 40.
There are no significant changes in epidemiology of musculoskeletal tumors in Shiraz, south of Iran, in comparison with other parts of the world.
肌肉骨骼肿瘤较为罕见，但任何地区关于它们的描述性数据对于降低死亡率和改善其治疗都很重要。
回顾性分析了设拉子大学骨科医院1997年至2008年的426份病理报告，该医院是伊朗南部肌肉骨骼肿瘤的主要转诊中心。我们收集并分析了关于肌肉骨骼肿瘤的年龄、性别、解剖部位和组织病理学类型的数据。
在426例病例中，男性占60.1%，女性占39.9%。最常见的恶性骨肿瘤是骨肉瘤（89例；50.6%）、转移瘤（30例；17.0%）、尤因肉瘤（28例；15.9%）和软骨肉瘤（14例；8.0%）。最常见的良性骨肿瘤是骨软骨瘤（136例；63.9%）、内生软骨瘤（23例；10.8%）、骨巨细胞瘤（21例；9.9%）和骨样骨瘤（14例；6.6%）。股骨是肌肉骨骼肿瘤最常累及的部位。良性肿瘤中其次是胫骨，恶性肿瘤中其次是肱骨。转移瘤（28例；32.6%）、软组织肿瘤（18例；20.9%）、骨软骨瘤（10例；11.6%）和骨肉瘤（9例；10.5%）是40岁以上患者中最常诊断出的骨病变。
与世界其他地区相比，伊朗南部设拉子的肌肉骨骼肿瘤流行病学没有显著变化。
