Information Network of Departments of Dermatology, University of Göttingen, Göttingen, Germany.
Allergy. 2012 Jul;67(7):847-57. doi: 10.1111/j.1398-9995.2012.02834.x. Epub 2012 May 7.
Contact allergy (CA) surveillance networks provide information to a multitude of stakeholders, which is indispensable for evidence-based decision-making in the field of prevention. Methods and results of the German surveillance system on CA are reviewed and discussed with reference to other systems. The German network structure comprises 56 departments of dermatology and includes all patients who are patch-tested for suspected CA. Data analysis considers the results of patch testing and further pertinent information for each patient. Following aspects are addressed: (i) the description of the clinical population, (ii) evaluation of patch test reactions, (iii) relationship between patch test results and population characteristics. Trend analyses on chromate (decreasing), epoxy resin (increasing) and nickel (heterogeneous) served as examples for surveillance system analyses, with the identification of sentinel events, as well as proof of success or failure of prevention. In addition, external data sources can be used such as sales data of patch test preparations to estimate frequencies of sensitization on a population level. National prescription data of drugs and statistics of labelling of preservatives on cosmetics can be included, the latter two approaches allowing for risk estimates conferred by specific allergens.
接触过敏（CA）监测网络为众多利益相关者提供信息，这对于预防领域的循证决策是不可或缺的。本文回顾和讨论了德国 CA 监测系统的方法和结果，并与其他系统进行了比较。德国网络结构由 56 个皮肤科部门组成，包括所有因疑似 CA 而接受斑贴试验的患者。数据分析考虑了每位患者的斑贴试验结果和其他相关信息。本文介绍了以下几个方面：（i）临床人群的描述，（ii）斑贴试验反应的评估，（iii）斑贴试验结果与人群特征之间的关系。以铬（减少）、环氧树脂（增加）和镍（异质）为例，对监测系统进行了分析，确定了预警事件，并证明了预防的成功或失败。此外，还可以使用外部数据源，如斑贴试验制剂的销售数据，以估计人群中致敏的频率。国家药物处方数据和化妆品中防腐剂标签的统计数据也可以包括在内，后两种方法可以评估特定过敏原带来的风险。
