Geier J, Lessmann H, Skudlik C, Ballmer-Weber B K, Weisshaar E, Uter W, Schnuch A
Informationsverbund Dermatologischer Kliniken (IVDK), Institut an der Universität Göttingen, Germany.
Abteilung Dermatologie, Umweltmedizin und Gesundheitstheorie, Universität Osnabrück und Institut für interdisziplinäre dermatologische Prävention und Rehabilitation (iDerm) an der Universität Osnabrück, Germany.
Allergol Select. 2017 Aug 4;1(2):127-140. doi: 10.5414/ALX01593E. eCollection 2017.
Occupational exposure of bricklayers, construction workers, tile setters etc. has changed during the last years. For some years now, all manually handled cement in the European Union and in Switzerland is chromate-reduced. Epoxy resin systems are being used in more and more fields of application. Improved worker's protection, especially wearing protective gloves, is promoted. These changes influence the spectrum of occupational contact sensitization.
Description of the current allergen spectrum in patients working in the building trade who suffer from occupational contact dermatitis.
Retrospective analysis of data of the Information Network of Departments of Dermatology (IVDK), 2009 - 2011.
During the study period, 245 bricklayers, construction workers, tile setters etc. with occupational dermatitis have been patch tested. Potassium dichromate was the most frequent allergen, yielding 15.1% positive reactions, followed by epoxy resin with 13.7% positive reactions. Beyond that, there were 8 additional components of epoxy resin systems (5 reactive diluents and 3 amine hardeners), as well as 9 rubber ingredients, mainly thiurams, among the 30 most frequent allergens. In the course of time, a decline of chromate sensitization could be noted, paralleled by a decline of cobalt sensitization. In contrast, sensitization to epoxy resin has increased.
Thanks to the usage of chromate-reduced cement, chromate sensitization continues to decline in the building trade. The increase of epoxy resin sensitization must prompt intensified prevention efforts. When recommending protective gloves, thiuram-free products should be preferred. The most important allergens are covered by the following test series recommended by the German Contact Dermatitis Research Group (DKG): DKG baseline series, DKG test series "building trade", DKG rubber series.
在过去几年中,砖匠、建筑工人、瓷砖安装工等的职业暴露情况发生了变化。如今在欧盟和瑞士,所有人工搬运的水泥都减少了铬酸盐含量。环氧树脂体系正被应用于越来越多的领域。人们提倡加强工人保护,尤其是佩戴防护手套。这些变化影响了职业性接触致敏的范围。
描述患有职业性接触性皮炎的建筑行业工人当前的过敏原谱。
对皮肤科部门信息网络(IVDK)2009 - 2011年的数据进行回顾性分析。
在研究期间,对245名患有职业性皮炎的砖匠、建筑工人、瓷砖安装工等进行了斑贴试验。重铬酸钾是最常见的过敏原,阳性反应率为15.1%,其次是环氧树脂,阳性反应率为13.7%。除此之外,在30种最常见的过敏原中,还有8种环氧树脂体系的成分(5种活性稀释剂和3种胺类固化剂),以及9种橡胶成分,主要是秋兰姆。随着时间的推移,可以注意到铬酸盐致敏率下降,同时钴致敏率也下降。相比之下,对环氧树脂的致敏率有所上升。
由于使用了低铬酸盐水泥,建筑行业中铬酸盐致敏率持续下降。环氧树脂致敏率的上升必须促使加强预防措施。在推荐防护手套时,应优先选择不含秋兰姆的产品。德国接触性皮炎研究组(DKG)推荐的以下试验系列涵盖了最重要的过敏原:DKG基础系列、DKG“建筑行业”试验系列、DKG橡胶系列。