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[梅毒螺旋体培养菌株抗原谱的免疫化学研究]

[An immunochemical study of the antigenic profile of cultured strains of Treponema pallidum].

作者信息

Rasskazov N I, Chalov V V, Chalova E I, Fomina T F

出版信息

Vestn Dermatol Venerol. 1990(8):42-5.

PMID:2256379
Abstract

Antigenic profile of T. pallidum culture strains was under study. To prove the presence of 'active' antigenic substances with antibodies in the blood sera of syphilitics, the authors have employed immunization with antigen preparation and reimmunization with antigen precipitate from syphilitics' blood sera. Crossed immunoelectrophoresis has detected up to 25 antigenic components in US-treated culture strains. Five of these contributed to the formation of the specific precipitate from syphilitics' blood sera pool.

摘要

正在研究梅毒螺旋体培养菌株的抗原谱。为了用梅毒患者血清中的抗体证明“活性”抗原物质的存在,作者采用了用抗原制剂进行免疫以及用梅毒患者血清中的抗原沉淀物进行再次免疫的方法。交叉免疫电泳已在经超声处理的培养菌株中检测到多达25种抗原成分。其中五种促成了梅毒患者血清池特异性沉淀物的形成。

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