Ohkawara H, Kitagawa T, Fukushima N, Ito T, Sawa Y, Yoshimine T
Medical Center for Translational Research, Osaka University Hospital, Osaka, Japan.
Transplant Proc. 2012 May;44(4):855-8. doi: 10.1016/j.transproceed.2012.02.023.
As there is only one skin procurement organization in Japan the Japan Skin Bank Network (JSBN), all skin grafts procured in Japan are sent by a commercialized delivery system. Preliminarily, bottles containing saline were transported in a cardboard box using a so-called "cooled home delivery service" using a truck with a refrigerated cargo container. During transportation the temperature in the cardboard box increased to 18°C in summer and decreased to -5°C in winter. For these reasons, we investigated whether a newly developed container "Medi Cube" would be useful to transport skin grafts.
Four bottles with a capacity of 300 mL containing 150 mL of saline in a Medi Cube container were transported from Osaka to the JSBN in Tokyo between 4 PM and 10 AM using a commercialized cooled home delivery service. Two bottles were transported in a Medi Cube container without phase change materials (PCM) in winter and summer, respectively. Another two bottles were transported in the Medi Cube with PCMs in winter. The temperatures inside saline, inside a transportation container, and outside the container, and air temperature were monitored continuously with a recordable thermometer.
The temperatures inside saline and inside a Medi Cube container were maintained between 3 and 6°C, even when the temperature outside the container increased during parking. The temperature inside a Medi Cube container without PCM decreased to -3°C when the inside of the cargo container was overcooled in winter. However, the temperatures inside saline and inside a Medi Cube container with PCM were between 3 and 6°C, even when the temperature outside the container decreased to below 0°C in winter.
A Medi Cube container with PCM provided a safe, easy, and cost-effective method for overnight transportation of skin grafts.
由于日本只有一个皮肤采集组织——日本皮肤银行网络（JSBN），日本采集的所有皮肤移植物均通过商业化递送系统运送。最初，装有生理盐水的瓶子被装在纸箱中，使用一辆带有冷藏货柜的卡车通过所谓的“冷藏送货上门服务”运输。在运输过程中，夏季纸箱内温度升至18°C，冬季降至 -5°C。基于这些原因，我们研究了一种新开发的容器“Medi Cube”是否有助于皮肤移植物的运输。
四个容量为300 mL、装有150 mL生理盐水的瓶子被放置在一个Medi Cube容器中，于下午4点至上午10点之间通过商业化冷藏送货上门服务从大阪运送到东京的JSBN。冬季和夏季分别有两个瓶子被放置在没有相变材料（PCM）的Medi Cube容器中运输。另外两个瓶子在冬季放置在装有PCM的Medi Cube中运输。使用可记录温度计连续监测生理盐水内部、运输容器内部、容器外部的温度以及气温。
即使在停车期间容器外部温度升高，生理盐水内部和Medi Cube容器内部的温度仍保持在3至6°C之间。在冬季，当货柜内部过度冷却时，没有PCM的Medi Cube容器内部温度降至 -3°C。然而，即使在冬季容器外部温度降至0°C以下时，装有PCM的生理盐水内部和Medi Cube容器内部的温度仍在3至6°C之间。
带有PCM的Medi Cube容器为皮肤移植物的过夜运输提供了一种安全、简便且经济高效的方法。
