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散射相函数光谱使从脂质乳剂体模和组织测量得到的反射光谱对设备检测几何形状敏感。

Scattering phase function spectrum makes reflectance spectrum measured from Intralipid phantoms and tissue sensitive to the device detection geometry.

作者信息

Kanick S C, Krishnaswamy V, Gamm U A, Sterenborg H J C M, Robinson D J, Amelink A, Pogue B W

出版信息

Biomed Opt Express. 2012 May 1;3(5):1086-100. doi: 10.1364/BOE.3.001086. Epub 2012 Apr 24.

DOI:10.1364/BOE.3.001086
PMID:22567598
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3342184/
Abstract

Reflectance spectra measured in Intralipid (IL) close to the source are sensitive to wavelength-dependent changes in reduced scattering coefficient ([Formula: see text]) and scattering phase function (PF). Experiments and simulations were performed using device designs with either single or separate optical fibers for delivery and collection of light in varying concentrations of IL. Spectral reflectance is not consistently linear with varying IL concentration, with PF-dependent effects observed for single fiber devices with diameters smaller than ten transport lengths and for separate source-detector devices that collected light at less than half of a transport length from the source. Similar effects are thought to be seen in tissue, limiting the ability to quantitatively compare spectra from different devices without compensation.

摘要

在靠近光源处的脂质乳剂（IL）中测量的反射光谱对约化散射系数（[公式：见正文]）和散射相函数（PF）中与波长相关的变化敏感。使用具有单根光纤或分开的光纤的设备设计进行了实验和模拟，用于在不同浓度的IL中传输和收集光。光谱反射率与IL浓度的变化并非始终呈线性关系，对于直径小于十个输运长度的单光纤设备以及在距离光源小于半个输运长度处收集光的分开的源 - 探测器设备，观察到了与PF相关的效应。类似的效应被认为在组织中也会出现，这限制了在没有补偿的情况下定量比较来自不同设备的光谱的能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0475/3342184/90eb872acb8c/boe-3-5-1086-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0475/3342184/80492ce6866c/boe-3-5-1086-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0475/3342184/5db476a889ce/boe-3-5-1086-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0475/3342184/9e34451b7faa/boe-3-5-1086-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0475/3342184/89e445d380c5/boe-3-5-1086-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0475/3342184/36153de60c53/boe-3-5-1086-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0475/3342184/90eb872acb8c/boe-3-5-1086-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0475/3342184/80492ce6866c/boe-3-5-1086-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0475/3342184/5db476a889ce/boe-3-5-1086-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0475/3342184/9e34451b7faa/boe-3-5-1086-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0475/3342184/89e445d380c5/boe-3-5-1086-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0475/3342184/36153de60c53/boe-3-5-1086-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0475/3342184/90eb872acb8c/boe-3-5-1086-g006.jpg

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