Dipartimento di Fisica e Astronomia dell'Università degli Studi di Firenze, Via G. Sansone 1, 50019 Sesto Fiorentino, Firenze, Italy.
Phys Med Biol. 2011 Jan 21;56(2):N21-8. doi: 10.1088/0031-9155/56/2/N01. Epub 2010 Dec 15.
Measurements of optical properties carried out at visible and NIR wavelengths on many samples of Intralipid 20% showed a high stability and surprisingly small batch-to-batch variations. Measurements have been carried out in a short time interval using samples from nine different batches with expiry dates spreading over ten years. For the specific reduced scattering coefficient, the values we have obtained, averaged over the nine batches, are 25.9, 21.2, and 18.4 mm(-1) at λ = 632.8, 751, and 833 nm, respectively, and the corresponding maximum deviations from the average were 2.2%, 1.1%, and 1.4%. For the absorption coefficient, we obtained values slightly smaller with respect to the absorption coefficient of pure water at 751 and 833 nm, and slightly larger at 632.8 nm. These results suggest that Intralipid 20% can be the first step towards a diffusive reference standard for tissue-simulating phantoms.
对许多 20%Intralipid 样本在可见和近红外波长下进行的光学特性测量显示出高度的稳定性和令人惊讶的小批次间变化。在短时间间隔内使用来自九个不同批次的样本进行了测量，这些样本的有效期分布在十年内。对于特定的散射系数，我们在九个批次中获得的平均值分别为 25.9、21.2 和 18.4mm-1，在 λ=632.8、751 和 833nm 处，相应的平均最大偏差为 2.2%、1.1%和 1.4%。对于吸收系数，我们在 751 和 833nm 处获得的值相对于纯水的吸收系数略小，而在 632.8nm 处略大。这些结果表明，20%Intralipid 可以成为组织模拟体模扩散参考标准的第一步。
