Donato Paulo, Coelho P, Santos C, Bernardes A, Caseiro-Alves F
University Clinic of Radiology, Coimbra University Hospital-Medical School, Coimbra, Portugal.
Surg Radiol Anat. 2012 Nov;34(9):805-10. doi: 10.1007/s00276-012-0976-1. Epub 2012 May 9.
The aim of this study was to investigate the correspondence between the coronary arterial anatomy and the supplied myocardium based on the proposed American Heart Association (AHA) 17-segment model.
Six human cadaveric hearts without signs of infarct were selectively injected with colored contrasted gelatin in the three major coronary arteries. After injection, the hearts were scanned by computed tomography (64-detector scanner LightSpeed VCT, GE Healthcare) with a collimation of 64 × 0.625 mm. Reconstructed image data were analyzed in order to evaluate the blood supply of each myocardial segment.
Coronary artery territory varies due to anatomy variations. Left anterior descending coronary artery (LAD) was the main vessel responsible for the myocardium blood supply in 11 segments. LAD contributed to the blood supply of all apical segments. Left circumflex (LCx) was the main coronary artery for the infero-anterior wall. Right coronary artery (RCA) contributed in all hearts for the blood supply of infero-septal segments. There was an important overlap between LAD and RCA territories at the infero-septal region and between LAD and LCx territories at the antero-lateral region.
In our experiment, LAD territory was larger than the AHA-proposed 17-segment model. The most specific segments were located at the anterior wall and supplied exclusively by LAD. No specific segment could be exclusively attributed to RCA or to LCx. Sometimes, LCx can be the most important artery for the blood supply of the inferior wall even if the origin of the posterior descending artery is the RCA.
本研究旨在基于美国心脏协会(AHA)提出的17节段模型,探讨冠状动脉解剖结构与所供应心肌之间的对应关系。
对6例无梗死迹象的人类尸体心脏,选择性地向三大冠状动脉内注射彩色对比明胶。注射后,使用准直为64×0.625 mm的计算机断层扫描(64排探测器扫描仪LightSpeed VCT,GE医疗集团)对心脏进行扫描。对重建后的图像数据进行分析,以评估每个心肌节段的血供情况。
由于解剖结构变异,冠状动脉供血区域有所不同。左前降支冠状动脉(LAD)是11个节段心肌血供的主要血管。LAD为所有心尖节段供血。左旋支(LCx)是下前壁的主要冠状动脉。右冠状动脉(RCA)在所有心脏中都为下间隔节段供血。在下心间隔区域,LAD和RCA供血区域之间以及在前外侧区域,LAD和LCx供血区域之间存在重要重叠。
在我们的实验中,LAD供血区域大于AHA提出的17节段模型。最具特异性的节段位于前壁,且仅由LAD供血。没有特定节段可完全归因于RCA或LCx。有时,即使后降支动脉起源于RCA,LCx也可能是下壁血供最重要的动脉。