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预测抑郁自杀意念者未来的自杀企图:一项长达 10 年的纵向研究。

Predicting future suicide attempts among depressed suicide ideators: a 10-year longitudinal study.

机构信息

Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver BC, Canada V6T 1Z4.

出版信息

J Psychiatr Res. 2012 Jul;46(7):946-52. doi: 10.1016/j.jpsychires.2012.04.009. Epub 2012 May 9.

Abstract

Suicidal ideation and attempts are a major public health problem. Research has identified many risk factors for suicidality; however, most fail to identify which suicide ideators are at greatest risk of progressing to a suicide attempt. Thus, the present study identified predictors of future suicide attempts in a sample of psychiatric patients reporting suicidal ideation. The sample comprised 49 individuals who met full DSM-IV criteria for major depressive disorder and/or dysthymic disorder and reported suicidal ideation at baseline. Participants were followed for 10 years. Demographic, psychological, personality, and psychosocial risk factors were assessed using validated questionnaires and structured interviews. Phi coefficients and point-biserial correlations were used to identify prospective predictors of attempts, and logistic regressions were used to identify which variables predicted future attempts over and above past suicide attempts. Six significant predictors of future suicide attempts were identified - cluster A personality disorder, cluster B personality disorder, lifetime substance abuse, baseline anxiety disorder, poor maternal relationship, and poor social adjustment. Finally, exploratory logistic regressions were used to examine the unique contribution of each significant predictor controlling for the others. Comorbid cluster B personality disorder emerged as the only robust, unique predictor of future suicide attempts among depressed suicide ideators. Future research should continue to identify variables that predict transition from suicidal thoughts to suicide attempts, as such work will enhance clinical assessment of suicide risk as well as theoretical models of suicide.

摘要

自杀意念和自杀企图是一个重大的公共卫生问题。研究已经确定了许多自杀风险因素;然而,大多数研究都未能确定哪些有自杀意念的人最有可能发展为自杀企图。因此,本研究在报告自杀意念的精神科患者样本中确定了未来自杀企图的预测因素。该样本包括 49 名符合 DSM-IV 重性抑郁障碍和/或恶劣心境障碍标准并在基线时报告自杀意念的个体。参与者随访了 10 年。使用经过验证的问卷和结构化访谈评估了人口统计学、心理学、人格和心理社会风险因素。Phi 系数和点二项式相关系数用于确定尝试的前瞻性预测因素,逻辑回归用于确定哪些变量在过去的自杀尝试之外预测未来的尝试。确定了六个未来自杀企图的显著预测因素 - 群 A 人格障碍、群 B 人格障碍、终生物质滥用、基线焦虑障碍、不良的母子关系和不良的社会适应。最后,探索性逻辑回归用于检查在控制其他因素的情况下每个显著预测因素的独特贡献。共患群 B 人格障碍是抑郁自杀意念者未来自杀企图的唯一稳健、独特的预测因素。未来的研究应继续确定从自杀意念到自杀企图的转变的预测变量,因为这项工作将增强对自杀风险的临床评估以及自杀理论模型。

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