Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
J Control Release. 2012 Jul 10;161(1):62-72. doi: 10.1016/j.jconrel.2012.04.032. Epub 2012 May 1.
Microemulsions have successfully proven themselves as useful vehicles for drugs through the different routes of administration because they can confer on drugs greater water solubility and bioavailability. The ability to understand the structural aspects of these important drug delivery systems is essential to the progress of this science. The use of NMR techniques in pharmaceutical and drug delivery science is increasing especially in the characterization field. This review demonstrates the major and novel NMR methods and techniques used in understanding and characterizing the different microemulsion components, types and structures.
微乳液已成功证明自己是通过不同给药途径将药物递送给患者的有用载体，因为它们可以使药物具有更大的水溶性和生物利用度。理解这些重要药物传递系统的结构方面对于该科学的发展至关重要。NMR 技术在制药和药物输送科学中的应用正在增加，特别是在表征领域。本文综述了用于理解和表征不同微乳液成分、类型和结构的主要和新型 NMR 方法和技术。
