Marwaha A S, Cockcroft D, Philipenko B
Internal Medicine, University of Saskatchewan, Canada.
Division of Respirology, Critical Care and Sleep Medicine, Department of Medicine, University of Saskatchewan, Canada.
Respir Med Case Rep. 2024 Sep 20;52:102110. doi: 10.1016/j.rmcr.2024.102110. eCollection 2024.
Metamucil®, a soluble fiber supplement for constipation, triggered new onset asthma symptoms in a 44-year-old sensitised nurse after a single inhaled exposure. After the initial event, she had no further exposures. She continued to face challenges with exacerbations, poor asthma control, and chronic cough. Despite 30 years of clinic follow-up, her asthma remained difficult to manage, requiring chronic prednisone. While tapering off corticosteroids, she developed polymyalgia rheumatica. This case underscores that psyllium in Metamucil® can cause reactions ranging from mild to severe, even with a single inhaled exposure, emphasising the need for caution in those without a history of asthma.
康赐尔（Metamucil®）是一种用于治疗便秘的可溶性纤维补充剂，一名44岁的过敏护士在单次吸入接触后出现了新发哮喘症状。首次接触后，她没有再次接触。她仍面临哮喘加重、哮喘控制不佳和慢性咳嗽等问题。尽管经过30年的门诊随访，她的哮喘仍难以控制，需要长期使用泼尼松。在逐渐减少皮质类固醇药物用量时，她患上了风湿性多肌痛。该病例强调，即使是单次吸入接触，康赐尔（Metamucil®）中的车前草也可能引起从轻度到重度的反应，这凸显了对无哮喘病史者需谨慎使用的必要性。
