Li Yaya, Du Jie, Yang Jiandong, Liu Dong, Lu Xiaoquan
Key Laboratory of Bioelectrochemistry & Environmental Analysis of Gansu Province, College of Chemistry & Chemical Engineering, Northwest Normal University, Lanzhou 730070, China.
Colloids Surf B Biointerfaces. 2012 Sep 1;97:32-6. doi: 10.1016/j.colsurfb.2012.03.029. Epub 2012 Apr 27.
Single-walled carbon nanotubes (SWCNTs) fabricated by sodium dodecyl sulfate (SDS) (f-SWCNTs) modified glassy carbon electrodes (f-SWCNTs/GCE) for the simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA). The f-SWCNTs/GCE displayed very good electrochemical catalytic activities with respect to GCE. The oxidation over-potentials of DA and UA decreased dramatically, and their oxidation peak currents increased significantly at f-SWCNTs/GCE compared to those obtained at the bare GCE. Simultaneously, the oxidation peak currents of AA decreased accordingly. The f-SWCNTs/GCE not only divide the overlapping voltammetric responses of them into individual voltammetric peaks, but also totally eliminate the interference from AA and distinguish DA from UA. The catalytic peak currents obtained from square-wave voltammetry increased linearly with increasing DA concentrations in the range of 5.0×10(-6) to 1.0×10(-4)M with a detection limit of 2.0×10(-8)M (S/N=3). The method was also successfully applied for determination of DA and showed good recovery in some biological fluids.
通过十二烷基硫酸钠（SDS）制备的单壁碳纳米管（SWCNTs）修饰玻碳电极（f-SWCNTs/GCE）用于同时测定抗坏血酸（AA）、多巴胺（DA）和尿酸（UA）。相对于玻碳电极（GCE），f-SWCNTs/GCE表现出非常好的电化学催化活性。与在裸玻碳电极上获得的结果相比，在f-SWCNTs/GCE上DA和UA的氧化过电位显著降低，它们的氧化峰电流显著增加。同时，AA的氧化峰电流相应降低。f-SWCNTs/GCE不仅将它们重叠的伏安响应分离为单独的伏安峰，而且完全消除了AA的干扰并区分了DA和UA。在5.0×10⁻⁶至1.0×10⁻⁴M范围内，方波伏安法获得的催化峰电流随DA浓度增加呈线性增加，检测限为2.0×10⁻⁸M（S/N = 3）。该方法也成功应用于DA的测定，并在一些生物流体中显示出良好的回收率。
