Diebold J, Temmim L
Sem Hop. 1979;55(17-18):925-8.
The histological classification of Hodgkin's disease, as proposed by Lunkes and Butler, is incomplete and does not include all the morphological findings. The distinction between sub-varieties of the nodular sclerosing type and particular forms of the disease (interfollicular with necrosis, with xanthelasma, or epithelioid pseudo-metastatic cells) clearly demonstrates the large polymorphism of the ganglionic lesions. A study of the different types encountered in the same patient shows that there is probably a form which evolves from type 1 towards type 3 and then type 4, an another form characterized by nodular sclerosis. The distribution of the various varieties and sub-varieties were studied by the author in 442 ganglia and results were similar to those reported in other series: nodular sclerosing form: 38.2%; form without nodular sclerosis: 61.8% made up of H1: 10.6%, H3: 45.5%, H4: 5.6%.
伦克斯(Lunkes)和巴特勒(Butler)提出的霍奇金病组织学分类并不完整,未涵盖所有形态学表现。结节硬化型的亚变种与该病的特定形式(伴有坏死的滤泡间型、伴有黄斑瘤或上皮样假转移细胞)之间的区别清楚地表明了淋巴结病变的高度多态性。对同一患者中遇到的不同类型进行研究表明,可能存在一种从1型向3型进而向4型演变的形式,以及另一种以结节硬化为特征的形式。作者对442个淋巴结中的各种变种和亚变种分布进行了研究,结果与其他系列报道相似:结节硬化型:38.2%;无结节硬化型:61.8%,其中H1型占10.6%,H3型占45.5%,H4型占5.6%。