Kuse R, Calavrezos A, Hinrichs A, Hausmann K
Dtsch Med Wochenschr. 1981 May 1;106(18):571-4. doi: 10.1055/s-2008-1070357.
Due to advantages of diagnostic and therapeutic progress the five-year-survival rates for 3 histological subtypes have become comparable in 322 patients with Hodgkin's disease during the years 1972 to 1979. Five-year-survival was 96% for the predominantly lymphocytic type, 90% for the nodular sclerosing type and 77% for the mixed cell type. Survival for all types together was 84% after 5 years and 80% after 7 years. The lymphocytic depletion type had a much worse prognosis with a five-year-survival of 31%. Apart from a reduced incidence of nodular sclerosis after the 40th year of life the histological forms were evenly spread between age groups and sexes On the other hand there were relationships between histological type and clinical stage.
由于诊断和治疗方面的进展,在1972年至1979年间的322例霍奇金病患者中,3种组织学亚型的五年生存率已变得相当。淋巴细胞为主型的五年生存率为96%,结节硬化型为90%,混合细胞型为77%。所有类型的总体五年生存率为84%,七年生存率为80%。淋巴细胞消减型的预后要差得多,五年生存率为31%。除40岁以后结节硬化的发病率有所降低外,各组织学类型在年龄组和性别之间分布均匀。另一方面,组织学类型与临床分期之间存在关联。