Isariyawongse Brandon K, Kattan Michael W
Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue/Q-10, Cleveland, OH 44195, USA.
Surg Oncol Clin N Am. 2012 Jul;21(3):439-47, viii-ix. doi: 10.1016/j.soc.2012.03.007. Epub 2012 Apr 17.
Artificial neural networks, prediction tables, and clinical nomograms allow physicians to transmit an immense amount of prognostic information in a format that exhibits comprehensibility and brevity. Current models demonstrate the feasibility to accurately predict many oncologic outcomes, including pathologic stage, recurrence-free survival, and response to adjuvant therapy. Although emphasis should be placed on the independent validation of existing prediction tools, there is a paucity of models in the literature that focus on quality of life outcomes. The unification of tools that predict oncologic and quality of life outcomes into a comparative effectiveness table will furnish patients with cancer with the information they need to make a highly informed and individualized treatment decision.
人工神经网络、预测表和临床列线图使医生能够以一种兼具易懂性和简洁性的形式传递大量预后信息。当前模型证明了准确预测许多肿瘤学结果的可行性,包括病理分期、无复发生存率和辅助治疗反应。尽管应强调对现有预测工具进行独立验证,但文献中关注生活质量结果的模型较少。将预测肿瘤学和生活质量结果的工具整合到一个比较有效性表中,将为癌症患者提供他们做出充分知情且个性化治疗决策所需的信息。