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在急诊室中,为排除肺栓塞而行 CT 肺动脉造影检查:证据与辩护。

Ordering CT pulmonary angiography to exclude pulmonary embolism: defense versus evidence in the emergency room.

机构信息

Department of Emergency Medicine, Inselspital, University Hospital Bern, Freiburgstrasse, 3010 Bern, Switzerland.

出版信息

Intensive Care Med. 2012 Aug;38(8):1345-51. doi: 10.1007/s00134-012-2595-z. Epub 2012 May 15.

Abstract

PURPOSE

To identify reasons for ordering computed tomography pulmonary angiography (CTPA), to identify the frequency of reasons for CTPA reflecting defensive behavior and evidence-based behavior, and to identify the impact of defensive medicine and of training about diagnosing pulmonary embolism (PE) on positive results of CTPA.

METHODS

Physicians in the emergency department of a tertiary care hospital completed a questionnaire before CTPA after being trained about diagnosing PE and completing questionnaires.

RESULTS

Nine hundred patients received a CTPA during 3 years. For 328 CTPAs performed during the 1-year study period, 140 (43 %) questionnaires were completed. The most frequent reasons for ordering a CTPA were to confirm/rule out PE (93 %), elevated D-dimers (66 %), fear of missing PE (55 %), and Wells/simplified revised Geneva score (53 %). A positive answer for "fear of missing PE" was inversely associated with positive CTPA (OR 0.36, 95 % CI 0.14-0.92, p = 0.033), and "Wells/simplified revised Geneva score" was associated with positive CTPA (OR 3.28, 95 % CI 1.24-8.68, p = 0.017). The proportion of positive CTPA was higher if a questionnaire was completed, compared to the 2-year comparison period (26.4 vs. 14.5 %, OR 2.12, 95 % CI 1.36-3.29, p < 0.001). The proportion of positive CTPA was non-significantly higher during the study period than during the comparison period (19.2 vs. 14.5 %, OR 1.40, 95 % CI 0.98-2.0, p = 0.067).

CONCLUSION

Reasons for CTPA reflecting defensive behavior-such as "fear of missing PE"-were frequent, and were associated with a decreased odds of positive CTPA. Defensive behavior might be modifiable by training in using guidelines.

摘要

目的

确定进行计算机断层肺动脉造影(CTPA)的原因,确定反映防御性和基于证据的行为的 CTPA 原因的频率,并确定防御性医疗和诊断肺栓塞(PE)培训对 CTPA 阳性结果的影响。

方法

在接受 PE 诊断培训并完成问卷后,三级医院急诊科的医生在进行 CTPA 前填写问卷。

结果

3 年间共有 900 例患者接受了 CTPA。在 3 年的研究期间进行了 328 次 CTPA,完成了 140 次(43%)问卷。进行 CTPA 的最常见原因是确认/排除 PE(93%)、D-二聚体升高(66%)、担心漏诊 PE(55%)和 Wells/简化修订日内瓦评分(53%)。对“担心漏诊 PE”的阳性回答与 CTPA 阳性呈负相关(OR 0.36,95%CI 0.14-0.92,p=0.033),而“Wells/简化修订日内瓦评分”与 CTPA 阳性相关(OR 3.28,95%CI 1.24-8.68,p=0.017)。与两年前的对比时期相比,如果完成了问卷,CTPA 阳性的比例更高(26.4%比 14.5%,OR 2.12,95%CI 1.36-3.29,p<0.001)。在研究期间,CTPA 阳性的比例虽不显著高于对比时期(19.2%比 14.5%,OR 1.40,95%CI 0.98-2.0,p=0.067)。

结论

反映防御性行为的 CTPA 原因(如“担心漏诊 PE”)很常见,与 CTPA 阳性的可能性降低有关。防御性行为可以通过使用指南进行培训来改变。

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