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一种用于 X 射线透视和锥形束 CT 引导手术的电磁“表中跟踪器”配置。

An electromagnetic "Tracker-in-Table" configuration for X-ray fluoroscopy and cone-beam CT-guided surgery.

机构信息

Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD, USA.

出版信息

Int J Comput Assist Radiol Surg. 2013 Jan;8(1):1-13. doi: 10.1007/s11548-012-0744-z. Epub 2012 May 15.

Abstract

PURPOSE

A novel electromagnetic tracking configuration was characterized and implemented for image-guided surgery incorporating C-arm fluoroscopy and/or cone-beam CT (CBCT). The tracker employed a field generator (FG) with an open rectangular aperture and a frame enclosure with two essentially hollow sides, yielding a design that presents little or no X-ray attenuation across the C-arm orbit. The "Window" FG (WFG) was characterized in comparison with a conventional "Aurora" FG (AFG), and a configuration in which the WFG was incorporated directly into the operating table was investigated in preclinical phantom studies.

METHOD

The geometric accuracy and field of view (FOV) of the WFG and AFG were evaluated in terms of target registration error (TRE) using an acrylic phantom on an (electromagnetic compatible) experimental bench. The WFG design was incorporated in a prototype operating table featuring a carbon fiber top beneath, which the FG could be translated for positioning under the patient. The X-ray compatibility was evaluated using a prototype mobile C-arm for fluoroscopy and CBCT in an anthropomorphic chest phantom. The susceptibility to EM field distortion associated with surgical tools (e.g., spine screws) and the C-arm itself was investigated in terms of TRE, and calibration methods were tested to provide robust image-world registration with minimal perturbation from the rotational C-arm.

RESULTS

The WFG demonstrated mean TRE of 1.28 ± 0.79 mm compared to 1.13 ± 0.72 mm for the AFG, with no statistically significant difference between the two (p = 0.32 and n = 250). The WFG exhibited a deeper field of view by ~10 cm providing an equivalent degree of geometric accuracy to a depth of z ~55 cm, compared to z ~45 cm for the AFG. Although the presence of a small number of spine screws did not degrade tracker accuracy, the mobile C-arm perturbed the electromagnetic field sufficiently to degrade TRE; however, a calibration method was identified to mitigate the effect. Specifically, the average calibration between posterior-anterior and lateral orientations of the C-arm was found to yield fairly robust registration for any C-arm pose with only a slight reduction in geometric accuracy (1.43 ± 0.31 mm in comparison with 1.28 ± 0.79 mm, p = 0.05). The WFG demonstrated reasonable X-ray compatibility, although the initial design of the window frame included suboptimal material and shape of the side bars that caused a level of streak artifacts in CBCT reconstructions. The streak artifacts were of sufficient magnitude to degrade soft-tissue visibility in CBCT but were negligible in the context of high-contrast imaging tasks (e.g., bone visualization).

CONCLUSION

The open frame of the WFG offers a potentially valuable configuration for electromagnetic trackers in image-guided surgery applications that are based on X-ray fluoroscopy and/or CBCT. The geometric accuracy and FOV are comparable to the conventional AFG and offers increased depth (z-direction) FOV. Incorporation directly within the operating table offers a streamlined implementation in which the tracker is in place but "invisible," potentially simplifying tableside logistics, avoidance of the sterile field, and compatibility with X-ray imaging.

摘要

目的

为了将 C 臂透视和/或锥形束 CT(CBCT)纳入图像引导手术,我们对一种新型电磁跟踪配置进行了特征描述和实现。该跟踪器采用具有开放式矩形孔径的场发生器(FG)和具有两个基本空心侧面的框架外壳,设计上在 C 臂轨道上几乎没有或没有 X 射线衰减。与传统的“极光”FG(AFG)相比,对“窗口”FG(WFG)进行了特征描述,并在临床前幻影研究中研究了将 WFG 直接集成到手术台上的配置。

方法

使用置于电磁兼容实验台上的丙烯酸体模,以靶标注册误差(TRE)评估 WFG 和 AFG 的几何精度和视野(FOV)。WFG 设计被集成到具有碳纤维顶部的原型手术台上,FG 可以在该手术台上平移以定位在患者下方。使用原型移动 C 臂在人体胸部幻影中进行透视和 CBCT,评估 X 射线兼容性。研究了与手术工具(例如脊柱螺钉)和 C 臂本身相关的电磁场所致失真的易感性,根据 TRE 测试了校准方法,并进行了测试,以提供具有最小旋转 C 臂干扰的稳健的图像世界注册。

结果

与 AFG 的 1.13 ± 0.72mm 相比,WFG 的平均 TRE 为 1.28 ± 0.79mm,两者之间没有统计学上的显著差异(p = 0.32,n = 250)。WFG 的视野更深,约为 10cm,在 z = 55cm 的深度提供了等效的几何精度,而 AFG 的视野为 z = 45cm。尽管少量脊柱螺钉的存在并未降低跟踪器的准确性,但移动 C 臂足以使电磁场失真,从而降低 TRE;但是,已经确定了一种校准方法来减轻该影响。具体来说,发现 C 臂前后向和侧向之间的平均校准对于任何 C 臂位置都能产生相当稳健的注册,仅略微降低了几何精度(1.43 ± 0.31mm 与 1.28 ± 0.79mm 相比,p = 0.05)。WFG 具有合理的 X 射线兼容性,尽管初始窗口框架设计包含次优的材料和侧面杆的形状,导致 CBCT 重建中出现条纹伪影。条纹伪影的幅度足以降低 CBCT 中的软组织可见度,但在高对比度成像任务(例如骨可视化)中则可以忽略不计。

结论

WFG 的开放式框架为基于 X 射线透视和/或 CBCT 的图像引导手术应用中的电磁跟踪器提供了一种潜在的有价值的配置。其几何精度和 FOV 与传统的 AFG 相当,并提供了更大的深度(z 方向)FOV。直接集成在手术台上提供了一种简化的实现方式,其中跟踪器就位但“不可见”,这可能简化了台边物流,避免了无菌区域,并与 X 射线成像兼容。

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