Adenis J P, Smolik I, Maes S
Service d'ophtalmologie, CHU Dupuytren, Limoges.
J Fr Ophtalmol. 1990;13(5):259-64.
The authors use injections of botulinum A toxin in treatment of facial spasms. 105 patients (70 patients with blepharospasm, 35 patients with hemispasm) were treated during 4 years. The toxin Wisconsin relieved spasms for an average of 10 weeks. Local complications such as ptosis and diplopia appeared in less than 1/5 of the cases. No general complications were observed. Repeated treatments are necessary. The authors noted a decrease of lacrimal secretion on the treated side in hemifacial spasm and concluded that botulinum A toxin injections could be used as a treatment of epiphora.
作者使用A型肉毒杆菌毒素注射治疗面部痉挛。在4年期间对105例患者（70例睑痉挛患者，35例偏侧痉挛患者）进行了治疗。威斯康星毒素使痉挛平均缓解10周。局部并发症如睑下垂和复视出现在不到五分之一的病例中。未观察到全身并发症。需要重复治疗。作者注意到偏侧面肌痉挛患者治疗侧泪液分泌减少，并得出结论，A型肉毒杆菌毒素注射可用于治疗溢泪症。
