Mohamad Nasir, Abd Halim Nurkhairul Nizam, Ahmad Rashidi, Baharuddin Kamarul Aryffin
Department of Emergency Medicine, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
Malays J Med Sci. 2009 Apr;16(2):33-7.
Theophylline toxicity is a life-threatening toxidrome that can present to an emergency department. To ascertain an immediate provisional diagnosis in toxicology at the emergency department is very challenging, especially when the patient presents with altered mental status, because the clinical features of several toxidromes overlap. We report a case of survival of undiagnosed theophylline toxicity that required intubation for two days in the intensive care unit. This was the first case to have been reported from our department. Accurate diagnosis of a toxidrome by gaining adequate history and conducting a thorough physical examination and early serum toxicology screening, coupled with good knowledge of toxicology, will lead to better patient outcomes.
茶碱中毒是一种可危及生命的中毒综合征,可出现在急诊科。在急诊科确定中毒的即时初步诊断极具挑战性,尤其是当患者出现精神状态改变时,因为几种中毒综合征的临床特征相互重叠。我们报告一例未被诊断出的茶碱中毒病例,该患者在重症监护病房需要插管两天。这是我们科室报告的首例此类病例。通过获取充分的病史、进行全面的体格检查和早期血清毒理学筛查,并结合对毒理学的充分了解来准确诊断中毒综合征,将带来更好的患者治疗结果。