Department of Chemical and Environmental Engineering, Graduate School of Engineering, Gunma University, Kiryu, Gunma, Japan.
J Biosci Bioeng. 2012 Aug;114(2):209-11. doi: 10.1016/j.jbiosc.2012.03.004. Epub 2012 May 15.
Four kinds of transporters, HXT1 and HXY7 from Saccharomyces cerevisiae, and GXF1 and GXS1 from Candida intermedia, were overexpressed in xylose-metabolizing S. cerevisiae harboring a xyloseisomerase-based pathway. Overexpression of transporter enhanced sugar consumption and ethanol production, and GXF1 was efficient for ethanol fermentation from both glucose and xylose.
四种转运蛋白,来自酿酒酵母的 HXT1 和 HXY7,以及中间假丝酵母的 GXF1 和 GXS1,在含有木糖异构酶途径的木糖代谢酿酒酵母中过表达。转运蛋白的过表达增强了糖的消耗和乙醇的生产,并且 GXF1 能够有效地从葡萄糖和木糖发酵生产乙醇。