Larik Ashfaq, Chiong Yi, Lee Lynn Chooi, Ng Yee Sien
Department of Rehabilitation Medicine, Singapore General Hospital, Singapore.
BMJ Case Rep. 2012 May 11;2012:bcr1220115378. doi: 10.1136/bcr.12.2011.5378.
Longitudinally extensive transverse myelitis (LETM) is usually associated with neuromyelitis optica and other autoimmune and inflammatory disorders but this is the first report linking it with dengue fever. Dengue infection can cause a variety of neurological complications which may result in poor recovery and long-term disability. The authors report here a patient who developed LETM in the para-infectious stage of dengue fever. The patient had a complicated clinical course resulting in severe paraparesis and urinary retention. Treatment with immunoglobulins and antiviral agents supported by a spell of early intensive rehabilitation programme produced excellent results in terms of recovery.
长节段横贯性脊髓炎（LETM）通常与视神经脊髓炎及其他自身免疫性和炎症性疾病相关，但这是首例将其与登革热联系起来的报告。登革热感染可导致多种神经系统并发症，可能导致恢复不佳和长期残疾。作者在此报告一名在登革热感染后阶段发生LETM的患者。该患者临床过程复杂，导致严重的双下肢轻瘫和尿潴留。免疫球蛋白和抗病毒药物治疗辅以早期强化康复计划取得了极佳的恢复效果。
