Jawairia Mahreema, Subhani Miral, Siddiqui Ghulam, Prasad Apsara, Shahzad Ghulamullah, Rizvon Kaleem, Mustacchia Paul
Department of Medicine, Nassau University Medical Center, East Meadow, NY 11554, USA.
Case Rep Gastrointest Med. 2012;2012:438525. doi: 10.1155/2012/438525. Epub 2012 Mar 15.
Cryptogenic cirrhosis (CC) is defined as cirrhosis occurring in an individual without an identifiable cause of liver disease, such as excessive alcohol consumption, viral hepatitis infection, hemochromatosis, autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, chronic intake of medications that could induce cirrhosis, alpha-1-antitrypsin deficiency, Wilson's disease, or any other rare cause of cirrhosis according to the clinical context. Cryptogenic cirrhosis is a common cause of liver-related morbidity and mortality in the United States. Nonalcoholic fatty liver disease is now recognized as the most common cause of cryptogenic cirrhosis. A biopsy specimen is also important for detecting histological advanced disease, which may be clinically silent and undetected by liver-related tests or diagnostic imaging. We are presenting an unusual case of a patient with cryptogenic cirrhosis found to have Kayser-Fleischer-like rings without evidence of Wilson's disease.
隐源性肝硬化（CC）定义为在没有可识别的肝病病因的个体中发生的肝硬化，这些病因包括过量饮酒、病毒感染性肝炎、血色素沉着症、自身免疫性肝炎、原发性胆汁性肝硬化、原发性硬化性胆管炎、长期服用可诱发肝硬化的药物、α-1抗胰蛋白酶缺乏症、威尔逊氏病，或根据临床情况的任何其他罕见的肝硬化病因。在美国，隐源性肝硬化是肝脏相关发病和死亡的常见原因。非酒精性脂肪性肝病现在被认为是隐源性肝硬化最常见的病因。活检标本对于检测组织学上的晚期疾病也很重要，这种疾病可能在临床上没有症状，并且通过肝脏相关检查或诊断成像无法检测到。我们报告了一例不寻常的隐源性肝硬化患者，该患者被发现有类似凯泽-弗莱舍尔环，但无威尔逊氏病的证据。
