• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肝病患者中的凯瑟-弗莱舍环。

Kayser-Fleischer-like rings in patients with hepatic disease.

机构信息

Department of Ophthalmology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Department of Gastroenterology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.

出版信息

Indian J Ophthalmol. 2021 May;69(5):1084-1087. doi: 10.4103/ij1o.IJO_438_20.

DOI:10.4103/ij1o.IJO_438_20
PMID:33913837
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8186623/
Abstract

PURPOSE

The aim of this work was to study Kayser-Fleischer [KF]-like rings in patients with hepatic or cholestatic liver disease and to find out the relation between serum bilirubin level and the presence of KF like ring in these patients.

METHODS

In this study, we evaluated patients with hepatic and cholestatic liver diseases with total Serum bilirubin levels >10 mg/dl. These patients were evaluated for the presence or absence of KF like ring.

RESULTS

A total of 67 patients with total bilirubin >10 mg/dl were included in the study. Patients were divided into 3 groups based on total S. bilirubin level: Group 1 with S. bilirubin >30 mg/dl, Group 2 with S. bilirubin >20 - <30 mg/dl and Group 3 with S. bilirubin >10 - <20 mg/dl at baseline evaluation. On follow-up they were divided into 3 groups based on the serum bilirubin level. Group 1- >20 mg/dl, Group 2- >10 - <20 mg/dl, Group 3- <10 mg/dl. KF like ring was seen in 98.5% of patients with high total S. bilirubin level. KF like ring disappeared in 87.5% of patients with reduction in the total S. bilirubin level to less than 10 mg/dl.

CONCLUSION

KF like ring was seen in 98.5% of patients with high total S. bilirubin, disappeared in 87.5% of patients with reduction in the total S. bilirubin level to less than 10 mg/dl. There was no significant difference between the Total S. bilirubin levels, age, gender and KF Like Ring.

摘要

目的

本研究旨在探讨肝性或胆汁淤积性肝病患者中出现凯-弗环(KF 环)的情况,并明确此类患者血清胆红素水平与 KF 环之间的关系。

方法

本研究共纳入总胆红素水平>10mg/dl 的肝性和胆汁淤积性肝病患者,评估其是否存在 KF 环。

结果

共纳入 67 例总胆红素>10mg/dl 的患者,根据总胆红素水平将患者分为 3 组:第 1 组总胆红素>30mg/dl,第 2 组总胆红素>20-<30mg/dl,第 3 组总胆红素>10-<20mg/dl。随访时根据血清胆红素水平将患者分为 3 组:第 1 组>20mg/dl,第 2 组>10-<20mg/dl,第 3 组<10mg/dl。高总胆红素水平患者中 98.5%存在 KF 环,当总胆红素水平降低至<10mg/dl 时,87.5%患者的 KF 环消失。

结论

高总胆红素水平患者中 98.5%存在 KF 环,当总胆红素水平降低至<10mg/dl 时,KF 环消失。总胆红素水平、年龄、性别与 KF 环之间无显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ec3/8186623/f394f688ea40/IJO-69-1084-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ec3/8186623/f394f688ea40/IJO-69-1084-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ec3/8186623/f394f688ea40/IJO-69-1084-g001.jpg

相似文献

1
Kayser-Fleischer-like rings in patients with hepatic disease.肝病患者中的凯瑟-弗莱舍环。
Indian J Ophthalmol. 2021 May;69(5):1084-1087. doi: 10.4103/ij1o.IJO_438_20.
2
Presence of pseudo-Kayser-Fleischer rings in patients without Wilson disease: a prospective cohort study.假性凯氏环在非威尔逊病患者中的存在:一项前瞻性队列研究。
Hepatol Commun. 2023 Apr 14;7(5). doi: 10.1097/HC9.0000000000000136. eCollection 2023 May 1.
3
Characteristics of neurological Wilson's disease without Kayser-Fleischer ring.无角膜 Kayser-Fleischer 环的神经型 Wilson 病的特征。
J Neurol Sci. 2012 Dec 15;323(1-2):183-6. doi: 10.1016/j.jns.2012.09.013. Epub 2012 Oct 5.
4
Evaluation and grading of Kayser-Fleischer ring in Wilson disease by Scheimpflug camera.应用 Scheimpflug 相机对肝豆状核变性患者的 Kayser-Fleischer 环进行评估和分级。
Eur J Ophthalmol. 2021 Jul;31(4):2116-2120. doi: 10.1177/1120672120931025. Epub 2020 Jun 9.
5
Advantages of Anterior Segment Optical Coherence Tomography Evaluation of the Kayser-Fleischer Ring in Wilson Disease.前段光学相干断层扫描评估威尔逊病中凯-弗环的优势
Cornea. 2017 Mar;36(3):343-346. doi: 10.1097/ICO.0000000000001126.
6
Is anterior segment OCT superior to slit-lamp biomicroscopic examination for Kayser Flesicher ring in Wilson's disease?前节 OCT 检查优于裂隙灯生物显微镜检查在威尔逊病中的 Kayser-Fleischer 环?
Eur Rev Med Pharmacol Sci. 2022 Jul;26(14):5178-5185. doi: 10.26355/eurrev_202207_29306.
7
Kayser-Fleischer ring as the presenting sign of Wilson disease.凯泽-弗莱舍尔环作为肝豆状核变性的首发体征。
Am J Ophthalmol. 2002 Jun;133(6):832-4. doi: 10.1016/s0002-9394(02)01408-3.
8
Anterior segment optical coherence tomography (AS-OCT) as a new method of detecting copper deposits forming the Kayser-Fleischer ring in patients with Wilson disease.前节光学相干断层扫描(AS-OCT)作为一种检测威尔逊病患者形成凯-弗环的铜沉积的新方法。
Acta Ophthalmol. 2019 Aug;97(5):e757-e760. doi: 10.1111/aos.14009. Epub 2019 Jan 11.
9
Wilson's disease: Experience at a tertiary care hospital.威尔逊病:一家三级医疗机构的经验
J Coll Physicians Surg Pak. 2013 Jul;23(7):525-6.
10
Fading Kayser-Fleischer ring revisited.再探褪色的凯-弗环。
Saudi J Ophthalmol. 2022 Feb 18;35(2):146-148. doi: 10.4103/1319-4534.337854. eCollection 2021 Apr-Jun.

引用本文的文献

1
Comparative evaluation of anterior segment optical coherence tomography and in vivo confocal microscopy for Kayser-Fleischer rings assessment in Wilson disease.眼前节光学相干断层扫描与体内共聚焦显微镜在威尔逊病凯-弗环评估中的比较评价
BMC Ophthalmol. 2025 Apr 15;25(1):209. doi: 10.1186/s12886-025-04032-9.
2
Performance of Relative Exchangeable Copper for the Diagnosis of Wilson Disease in Acute Liver Failure.相对可交换铜在急性肝衰竭中诊断威尔逊病的性能
J Inherit Metab Dis. 2025 Mar;48(2):e70024. doi: 10.1002/jimd.70024.
3
Commentary: Kayser-Fleischer-like rings in patients with hepatic disease.

本文引用的文献

1
Evaluation of Kayser-Fleischer ring in Wilson disease by anterior segment optical coherence tomography.通过眼前节光学相干断层扫描评估肝豆状核变性中的凯-弗环。
Indian J Ophthalmol. 2017 May;65(5):354-357. doi: 10.4103/ijo.IJO_400_16.
2
Kayser-Fleischer rings or bile pigment rings?凯泽-弗莱舍尔环还是胆色素环?
Indian J Gastroenterol. 2015 Sep;34(5):410-2. doi: 10.1007/s12664-015-0603-2.
3
Unexplained findings of kayser-fleischer-like rings in a patient with cryptogenic cirrhosis.隐源性肝硬化患者出现类似凯泽-弗莱舍尔环的不明原因表现。
评论:肝病患者中的凯泽-弗莱舍尔样环
Indian J Ophthalmol. 2021 May;69(5):1088. doi: 10.4103/ijo.IJO_3510_20.
Case Rep Gastrointest Med. 2012;2012:438525. doi: 10.1155/2012/438525. Epub 2012 Mar 15.
4
Kayser-Fleischer ring.凯泽-弗莱舍尔环。
J Postgrad Med. 2008 Jul-Sep;54(3):238-40. doi: 10.4103/0022-3859.41816.
5
Kayser-Fleischer like rings in alcoholic liver disease: a case report.酒精性肝病中的凯泽-弗莱舍尔样环:一例报告
Eur J Gastroenterol Hepatol. 2003 Jan;15(1):91-3. doi: 10.1097/00042737-200301000-00016.
6
Fluctuating Kayser-Fleischer-like rings in a jaundiced patient.一名黄疸患者出现波动的类凯-弗环。
Arch Intern Med. 1981 Feb;141(2):246-7.
7
Corneal icterus resulting from stromal bilirubin deposition.由基质胆红素沉积导致的角膜黄疸。
Ophthalmology. 1989 Aug;96(8):1212-4. doi: 10.1016/s0161-6420(89)32750-3.
8
Kayser-Fleischer like ring in autoimmune chronic active hepatitis.自身免疫性慢性活动性肝炎中的凯泽尔-弗莱舍尔样环。
Indian J Gastroenterol. 1991 Jul;10(3):101-2.
9
Pigmented corneal rings in non-Wilsonian liver disease.非威尔逊氏肝病中的角膜色素环
Ann Intern Med. 1977 Mar;86(3):285-8. doi: 10.7326/0003-4819-86-3-285.
10
Kayser-Fleischer-like rings in patients without Wilson's disease.无威尔逊病患者出现类似凯泽尔-弗莱舍尔环。
Gastroenterology. 1977 Jun;72(6):1331-5.