Department of Dermatology Department of Pathology, Hospital La Paz, Paseo de la Castellana 261, Madrid, Spain.
Int J Dermatol. 2012 Jun;51(6):722-5. doi: 10.1111/j.1365-4632.2011.05339.x.
Verrucous carcinoma (VC) of the anogenital area is an uncommon variant of squamous cell carcinoma (SCC). Its treatment is not standardized, but surgical excision must be performed if possible. The traditional approach does not distinguish between conventional SCC and VC, despite the extremely low metastatic potential of VC. Accordingly, most patients reported in the literature have been treated with radical surgery, including regional lymphadenectomy.
We report two cases in order to describe the oncologic, functional, and esthetic results achieved by Mohs micrographic surgery (MMS) in the treatment of this disease.
Good functional and esthetic results were achieved in both patients. No local or nodal relapses were detected during the respective 12- and 27-month follow-ups.
Early recognition of VC and the proper evaluation of deep biopsies will avoid misdiagnosis as SCC and may prevent the occurrence of unnecessary disfiguring interventions. The MMS technique may be considered as a surgical approach in genitoanal VC, although further research is required to confirm this.
肛门生殖器区域的疣状癌（VC）是鳞状细胞癌（SCC）的一种罕见变异。如果可能，必须进行手术切除来治疗。尽管 VC 的转移潜能极低，但传统方法并未区分普通 SCC 和 VC。因此，文献中报道的大多数患者都接受了根治性手术，包括区域淋巴结切除术。
我们报告了两例病例，以描述Mohs 显微外科手术（MMS）在治疗这种疾病时所取得的肿瘤学、功能和美学结果。
两名患者均取得了良好的功能和美学效果。在各自 12 个月和 27 个月的随访期间，均未发现局部或淋巴结复发。
早期识别 VC 和对深部活检的正确评估可避免误诊为 SCC，并可能防止不必要的毁容干预。MMS 技术可被视为治疗生殖器 VC 的一种手术方法，但需要进一步研究来证实这一点。
