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1
Controlling pain and reducing misuse of opioids: ethical considerations.控制疼痛和减少阿片类药物滥用:伦理考量。
Can Fam Physician. 2012 Apr;58(4):381-5, e190-5.
2
'I just need an opiate refill to get me through the weekend'.“我只需要开点鸦片类药物的镇痛剂来撑过这个周末”。
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Opioid prescribing practices after posterior spinal arthrodesis for adolescent idiopathic scoliosis.青少年特发性脊柱侧弯后路脊柱融合术后的阿片类药物处方实践。
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Opioid pharmacovigilance: A clinical-social history of the changes in opioid prescribing for patients with co-occurring chronic non-cancer pain and substance use.阿片类药物药物警戒:同时患有慢性非癌痛和物质使用障碍的患者阿片类药物处方变化的临床-社会史。
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引用本文的文献

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Concomitant use of opioid medications with triptans or serotonergic antidepressants in US office-based physician visits.在美国门诊医生诊疗中阿片类药物与曲坦类药物或5-羟色胺能抗抑郁药的联合使用情况。
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4
Opioid misuse in gastroenterology and non-opioid management of abdominal pain.胃肠道疾病阿片类药物滥用与腹痛的非阿片类药物管理
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Patient therapeutic education: placing the patient at the centre of the WHO analgesic ladder.患者治疗教育:将患者置于世界卫生组织止痛阶梯的中心位置。
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本文引用的文献

1
Survey of Ontario primary care physicians' experiences with opioid prescribing.安大略省初级保健医生阿片类药物处方经验调查。
Can Fam Physician. 2011 Mar;57(3):324-32.
2
Clustering of opioid prescribing and opioid-related mortality among family physicians in Ontario.安大略省家庭医生的阿片类药物处方和阿片类相关死亡率聚类。
Can Fam Physician. 2011 Mar;57(3):e92-6.
3
Assessing the prevalence of nonmedical prescription opioid use in the general Canadian population: methodological issues and questions.评估加拿大普通人群中非医疗处方类阿片类药物使用的流行率:方法学问题与疑问。
Can J Psychiatry. 2010 Sep;55(9):606-9. doi: 10.1177/070674371005500909.
4
Opioids for chronic noncancer pain: a new Canadian practice guideline.用于慢性非癌性疼痛的阿片类药物:加拿大新的实践指南。
CMAJ. 2010 Jun 15;182(9):923-30. doi: 10.1503/cmaj.100187. Epub 2010 May 3.
5
Nonmedical use of opioid analgesics among Ontario students.安大略省学生阿片类镇痛药的非医疗使用。
Can Fam Physician. 2010 Mar;56(3):256-62.
6
Long-term opioid management for chronic noncancer pain.慢性非癌性疼痛的长期阿片类药物管理
Cochrane Database Syst Rev. 2010 Jan 20;2010(1):CD006605. doi: 10.1002/14651858.CD006605.pub2.
7
Opioid prescriptions for chronic pain and overdose: a cohort study.慢性疼痛和阿片类药物处方与过量用药:队列研究。
Ann Intern Med. 2010 Jan 19;152(2):85-92. doi: 10.7326/0003-4819-152-2-201001190-00006.
8
Prescribing of opioid analgesics and related mortality before and after the introduction of long-acting oxycodone.在长效羟考酮推出前后,阿片类镇痛药的处方和相关死亡率。
CMAJ. 2009 Dec 8;181(12):891-6. doi: 10.1503/cmaj.090784. Epub 2009 Dec 7.
9
How many people in Canada use prescription opioids non-medically in general and street drug using populations?加拿大有多少人在一般情况下和在使用街头毒品的人群中非医疗目的使用处方类阿片?
Can J Public Health. 2009 Mar-Apr;100(2):104-8. doi: 10.1007/BF03405516.
10
Changing patterns in opioid addiction: characterizing users of oxycodone and other opioids.阿片类药物成瘾模式的变化:对羟考酮及其他阿片类药物使用者的特征分析
Can Fam Physician. 2009 Jan;55(1):68-9, 69.e1-5.

控制疼痛和减少阿片类药物滥用:伦理考量。

Controlling pain and reducing misuse of opioids: ethical considerations.

机构信息

Northern Ontario School of Medicine, Lakehead University, Thunder Bay, Ont.

出版信息

Can Fam Physician. 2012 Apr;58(4):381-5, e190-5.

PMID:22611604
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3325448/
Abstract

OBJECTIVE

To help family physicians achieve an ethical balance in their opioid prescribing practices.

QUALITY OF EVIDENCE

MEDLINE was searched for English-language articles published between 1985 and 2011. Most available evidence was level III.

MAIN MESSAGE

It is essential to follow practice guidelines when prescribing opioids, except when another course of action is demonstrably justified. In addition, when considering the appropriateness of an opioid prescription, with its many ethical implications, the decision can be usefully guided by the application of the ethical principles of beneficence, nonmaleficence, respect for autonomy, and justice. As well, it is essential to keep current about legal and regulatory changes and provincial electronic registries of opioid prescriptions.

CONCLUSION

Physicians need to ensure that their patients' pain is properly assessed and managed. Reaching optimal pain control might necessitate prescribing opioids. But the obligation to provide pain relief needs to be balanced with an equally important responsibility not to expose patients to risk of addiction and not to create opportunities for drug diversion, trafficking, and the addiction of others. Basic ethical principles can provide a framework to help physicians make ethically appropriate decisions about opioid prescribing.

摘要

目的

帮助家庭医生在开具阿片类药物处方时实现伦理平衡。

证据质量

检索了 1985 年至 2011 年间发表的英文医学文献。大多数现有证据为 III 级。

主要信息

除了有明显理由证明采取其他行动外,在开具阿片类药物时遵循实践指南至关重要。此外,在考虑开具阿片类药物处方的适当性时,鉴于其涉及许多伦理问题,应用有利、不伤害、尊重自主权和公正等伦理原则可以为决策提供有益指导。此外,还必须了解有关法律和法规的变化以及省级阿片类药物处方电子登记册。

结论

医生需要确保患者的疼痛得到适当评估和管理。实现最佳疼痛控制可能需要开具阿片类药物。但是,提供疼痛缓解的义务需要与同样重要的责任相平衡,即不使患者面临成瘾风险,不创造药物转移、贩运和他人成瘾的机会。基本伦理原则可以为医生提供一个框架,帮助他们就阿片类药物处方做出符合伦理的决策。