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男性乳腺囊内乳头状癌。探寻这种罕见疾病的最佳治疗方法。

Intracystic Papillary Carcinoma of the Breast in Males. In Search of the Optimal Treatment for this Rare Disease.

作者信息

Stamatakos Michael, Stefanaki Charikleia, Stasinou Theodora, Papantoni Evaggelia, Alexiou Ioannis, Kontzoglou Konstantinos

机构信息

4th Department of Surgery, University of Athens, Laiko General Hospital, Athens, Greece.

出版信息

Breast Care (Basel). 2011 Oct;6(5):399-403. doi: 10.1159/000331386. Epub 2011 Sep 26.

DOI:10.1159/000331386
PMID:22619652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3357144/
Abstract

Intracystic papillary carcinoma (IPC) of the breast in men is an extremely infrequent disease, and it appears to have a good prognosis. Because of this, histological findings are of great importance in the decision-making process regarding treatment. Clinical examination, radiological and histological assessments are required for early detection. Adequate surgical excision with negative margins is mandatory. However, the role of sentinel node biopsy has not been evaluated in male IPC. It appears that sentinel node biopsy may be an excellent alternative to radical axillary dissection in patients with IPC and associated ductal carcinoma in situ or invasive carcinoma. Nevertheless, due to the rarity of IPC and its confusing histopathological classification and staging, there are still no clear guidelines as far as IPC treatment is concerned.

摘要

男性乳腺囊内乳头状癌(IPC)是一种极为罕见的疾病,似乎预后良好。因此,组织学检查结果在治疗决策过程中至关重要。早期检测需要进行临床检查、放射学和组织学评估。必须进行切缘阴性的充分手术切除。然而,前哨淋巴结活检在男性IPC中的作用尚未得到评估。对于患有IPC以及相关原位导管癌或浸润性癌的患者,前哨淋巴结活检似乎可能是腋窝根治性清扫术的绝佳替代方案。尽管如此,由于IPC罕见且其组织病理学分类和分期令人困惑,就IPC的治疗而言,目前仍没有明确的指南。

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本文引用的文献

1
Intracystic papillary carcinoma in a male as a rare presentation of breast cancer: a case report and literature review.男性乳腺囊内乳头状癌:一种罕见的乳腺癌表现形式——病例报告及文献综述
J Med Case Rep. 2009 Jan 13;3:13. doi: 10.1186/1752-1947-3-13.
2
Intracystic papillary carcinoma: a review of 917 cases.囊内乳头状癌:917例病例回顾
Cancer. 2008 Sep 1;113(5):916-20. doi: 10.1002/cncr.23723.
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Intracystic papillary carcinoma associated with ductal carcinoma in situ in a male breast.男性乳腺囊内乳头状癌伴导管原位癌
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Papillary carcinoma in a male breast cyst: a diagnostic challenge.男性乳腺囊肿中的乳头状癌:一项诊断挑战。
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Am J Surg Pathol. 2006 Aug;30(8):1002-7. doi: 10.1097/00000478-200608000-00011.
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Comparison of MDCT and MRI for evaluating the intraductal component of breast cancer.多层螺旋CT(MDCT)与磁共振成像(MRI)在评估乳腺癌导管内成分中的比较。
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