Rafia Saman, Taghipour-Bazargani Taghi, Asadi Farzad, Vajhi Alireza, Bokaie Saied
Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran 14155-6453.
Am J Vet Res. 2012 Jun;73(6):830-7. doi: 10.2460/ajvr.73.6.830.
To determine alterations of serum biochemical variables in relation to changes of near- and far-field mean grayscale histogram (MGSH) and attenuation rates in liver ultrasonograms of periparturient cows.
67 Holstein cows.
Cows were allocated on the basis of body condition score into underconditioned (n = 21), moderately conditioned (23), and overconditioned (23) groups. Serum samples (obtained every 10 days from 30 days before to 30 days after calving) were analyzed for aspartate aminotransferase, alanine aminotransferase, and γ-glutamyltransferase activities and BUN, albumin, calcium, and inorganic phosphorus concentrations along with digital estimation of near- and far-field MGSH values of liver ultrasonograms and deep attenuation. Values were compared among groups and within each group, and their correlations were determined in the pre- and postpartum periods.
Serum biochemical variables did not differ significantly among groups. Aspartate aminotransferase and γ-glutamyltransferase activities increased in the postpartum period. Fluctuations of alanine aminotransferase activity were not significant; BUN decreased significantly in the peripartum period. Albumin concentration decreased prior to parturition and remained low, but significantly increased after parturition. Calcium concentration decreased on day 10 but subsequently increased. Phosphorus concentration decreased stepwise until day 10 after calving. Postpartum biochemical variables had weak correlations with near- and far-field MGSH values in overconditioned cows. The highest levels of sound attenuation were found in overconditioned cows on calving day.
Liver ultrasonographic features were poorly correlated with changes of serum biochemical variables. This suggests that liver ultrasonography is not a good technique for estimating functional liver abnormalities in periparturient cows.
确定围产期奶牛肝脏超声检查中近场和远场平均灰度直方图（MGSH）及衰减率变化相关的血清生化指标的改变。
67头荷斯坦奶牛。
根据体况评分将奶牛分为体况差组（n = 21）、体况中等组（23头）和体况好组（23头）。在产犊前30天至产后30天期间，每隔10天采集血清样本，分析天冬氨酸转氨酶、丙氨酸转氨酶和γ-谷氨酰转移酶活性以及尿素氮、白蛋白、钙和无机磷浓度，同时对肝脏超声检查的近场和远场MGSH值及深部衰减进行数字评估。比较各组间及每组内的值，并确定产前和产后各期它们之间的相关性。
各组间血清生化指标差异不显著。产后天冬氨酸转氨酶和γ-谷氨酰转移酶活性升高。丙氨酸转氨酶活性波动不显著；围产期尿素氮显著降低。白蛋白浓度在分娩前下降并维持在低水平，但产后显著升高。钙浓度在第10天下降，但随后升高。磷浓度在产犊后第10天前逐步下降。在体况好的奶牛中，产后生化指标与近场和远场MGSH值的相关性较弱。在产犊当天，体况好的奶牛的声衰减水平最高。
肝脏超声特征与血清生化指标变化的相关性较差。这表明肝脏超声检查不是评估围产期奶牛肝脏功能异常的良好技术。
