Komosinski Maciej
Institute of Computing Science, Poznan University of Technology, Piotrowo 2, 60-965 Poznan, Poland.
Theory Biosci. 2012 Jun;131(2):103-16. doi: 10.1007/s12064-012-0153-4. Epub 2012 May 25.
This article presents properties of the clock-counter model with a periodic generator employed as the source of regularly emitted pulses. The pacemaker and accumulator mechanisms are often considered in research in neurobiology and cognitive science: neurons or their groups serve as oscillators, and the number of spikes emitted while a stimulus lasts becomes an estimate of the length of the stimulus. The article integrates three approaches: a theoretical model to present the general concept, a working implementation of this model to perform intensive simulation experiments, and the analytical description of the behavior of the model. Oscillators that exhibit some degree of regularity have been compared to the Poisson ones, and the corresponding probability distributions have been presented that describe the number of pulses accumulated over time. Several continuous and discrete interpulse distributions have been investigated, and the influence of generator parameters on the possible outcomes of the measurement have been described. Particular attention has been paid to the relationship between measurement variability and the mean number of pulses observed. Issues concerning practical realizations of periodic generators: discrete time, dependence of the generator start time on the stimulus, and relation to Weber's law have been discussed as well.
本文介绍了具有周期性发生器的时钟 - 计数器模型的特性,该周期性发生器用作定期发射脉冲的源。起搏器和累加器机制在神经生物学和认知科学研究中经常被考虑:神经元或其群体充当振荡器,刺激持续期间发射的尖峰数量成为刺激长度的估计值。本文整合了三种方法:用于呈现一般概念的理论模型、用于执行密集模拟实验的该模型的实际实现,以及对模型行为的分析描述。已将表现出一定程度规律性的振荡器与泊松振荡器进行了比较,并给出了描述随时间累积的脉冲数量的相应概率分布。已研究了几种连续和离散的脉冲间隔分布,并描述了发生器参数对测量可能结果的影响。特别关注了测量变异性与观察到的平均脉冲数之间的关系。还讨论了与周期性发生器实际实现相关的问题:离散时间、发生器启动时间对刺激的依赖性以及与韦伯定律的关系。