Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore 168751, Singapore.
Best Pract Res Clin Endocrinol Metab. 2012 Jun;26(3):303-11. doi: 10.1016/j.beem.2012.03.011. Epub 2012 Apr 30.
Most patients with Graves' orbitopathy have mild disease that requires no or minimal intervention. For the minority of patients with moderate or severe disease, multiple medical and surgical treatments may be required at different stages. It is crucial that such patients are monitored closely and treatments applied with care in the right sequence. Medical treatments should be used as early as possible and only during the active phase of the disease. Rehabilitative surgery is indicated in the inactive phase of the disease and should follow the sequence: surgical decompression followed by eye muscle surgery, followed by lid surgery. Delivery of care in a coordinated fashion that makes use of best available expertise is important and best implemented through a Combined Thyroid Eye clinic.
大多数 Graves 眼病患者的疾病处于轻度,不需要或只需最小程度的干预。对于少数中度或重度疾病患者,可能需要在不同阶段采用多种药物和手术治疗。密切监测此类患者并谨慎地按正确顺序应用治疗非常重要。应尽早使用药物治疗,并且只在疾病的活动期使用。在疾病的非活动期,可采用康复性手术,手术顺序为:减压手术、眼外肌手术、眼睑手术。以协调方式提供护理,利用现有最佳专业知识非常重要,最好通过甲状腺眼病联合门诊来实施。