Dipartimento di Scienze Neurologiche, IRCCS Institute of Neurological Sciences of Bologna, University of Bologna, Via Ugo Foscolo 7, 40123 Bologna, Italy.
Curr Pain Headache Rep. 2012 Oct;16(5):477-83. doi: 10.1007/s11916-012-0281-z.
Comorbidity may be defined as the association of two or more diseases in individuals at a frequency greater than that expected statistically by chance. Studying the co-occurrence of two disorders requires a careful statistical analysis before any clear conclusion on causality is reached. Many studies have looked for an association between migraine and many diseases, reporting several sometimes controversial comorbidities in migraine subjects. Although migraine is more common in women than in men, very few studies have analyzed the comorbidity of perimenstrual migraine, a migraine sub-type characterized by attacks of migraine without aura related to menstruation. We review the studies on migraine comorbidities, particularly migraine without aura in women.
共病可以定义为个体中两种或多种疾病的关联,其发生频率高于统计学上的偶然机会。在得出任何关于因果关系的明确结论之前,研究两种疾病的同时发生需要进行仔细的统计分析。许多研究都在寻找偏头痛与许多疾病之间的关联,报告了偏头痛患者中存在几种有时存在争议的共病。尽管偏头痛在女性中比在男性中更为常见,但很少有研究分析经前期偏头痛的共病,这种偏头痛亚型的特点是与月经相关的无先兆偏头痛发作。我们回顾了偏头痛共病的研究,特别是女性无先兆偏头痛。