Sapienza University, Advanced Molecular Diagnostic Unit, NESMOS Department, Sant'Andrea Hospital, Rome, Italy.
Curr Pain Headache Rep. 2012 Oct;16(5):445-51. doi: 10.1007/s11916-012-0280-0.
Pure menstrual migraine (PMM) and menstrually related migraine (MRM) are difficult challenges in migraine management. Triptans are a class of highly selective serotonin receptor agonists, which interfere with the pathogenesis of migraine and are effective in relieving the associated neurovegetative symptoms. In recent years triptans have been extensively proposed for the treatment of severe, disabling, and recurrent perimenstrual migraine attacks. This review summarizes the different levels of recommendations for the use of triptans in the treatment of perimenstrual migraine. This review is also intended to offer an updated reasonable guide to physicians treating perimenstrual migraine in daily practice.
单纯性经期偏头痛（PMM）和与经期相关的偏头痛（MRM）是偏头痛管理中的难题。曲坦类药物是一类高度选择性 5-羟色胺受体激动剂，可干扰偏头痛的发病机制，对缓解相关的自主神经症状有效。近年来，曲坦类药物广泛用于治疗严重、致残和复发性经前期偏头痛发作。本综述总结了曲坦类药物治疗经前期偏头痛的不同推荐级别。本综述还旨在为治疗经前期偏头痛的医生在日常实践中提供一个更新的合理指导。
