Davies Jamie A, Little Melissa H, Aronow Bruce, Armstrong Jane, Brennan Jane, Lloyd-MacGilp Sue, Armit Chris, Harding Simon, Piu Xinjun, Roochun Yogmatee, Haggarty Bernard, Houghton Derek, Davidson Duncan, Baldock Richard
University of Edinburgh, Hugh Robson Building, Edinburgh, UK.
Methods Mol Biol. 2012;886:185-201. doi: 10.1007/978-1-61779-851-1_17.
The Genitourinary Development Molecular Atlas Project (GUDMAP) aims to document gene expression across time and space in the developing urogenital system of the mouse, and to provide access to a variety of relevant practical and educational resources. Data come from microarray gene expression profiling (from laser-dissected and FACS-sorted samples) and in situ hybridization at both low (whole-mount) and high (section) resolutions. Data are annotated to a published, high-resolution anatomical ontology and can be accessed using a variety of search interfaces. Here, we explain how to run typical queries on the database, by gene or anatomical location, how to view data, how to perform complex queries, and how to submit data.
泌尿生殖系统发育分子图谱项目(GUDMAP)旨在记录小鼠泌尿生殖系统发育过程中基因在时间和空间上的表达情况,并提供各种相关的实用和教育资源。数据来自微阵列基因表达谱分析(来自激光切割和荧光激活细胞分选样本)以及低分辨率(整体装片)和高分辨率(切片)的原位杂交。数据被注释到已发表的高分辨率解剖本体论中,并可通过各种搜索界面进行访问。在这里,我们将解释如何通过基因或解剖位置在数据库上运行典型查询、如何查看数据、如何执行复杂查询以及如何提交数据。