Connor S E J, Siddiqui A, O'Gorman R, Tysome J R, Lee A, Jiang D, Fitzgerald-O'Connor A
Department of Radiology, Guy's and St Thomas' Hospital, London, UK.
J Laryngol Otol. 2012 Jun;126(6):586-93. doi: 10.1017/S0022215112000606.
(1) To study the prevalence and characteristics of large endolymphatic sac internal compartments on thin-section T2- and T2*-weighted magnetic resonance imaging, and to relate these to other large endolymphatic sac magnetic resonance imaging features, and (2) to correlate the compartment imaging features, endolymphatic sac size and labyrinthine anomalies with the patients' clinical and audiological data.
Magnetic resonance imaging studies for 38 patients with large endolymphatic sac anomalies were retrospectively reviewed in a tertiary referral centre. Endolymphatic sac compartment presence, morphology and imaging signal were assessed. Endolymphatic sac size and labyrinthine anomalies were also recorded. Endolymphatic sac compartments and other imaging features were correlated with clinical and audiological data.
Compartments were present in 57 per cent of the imaged endolymphatic sacs, but their presence alone did not correlate with other imaging features or clinical data. The endolymphatic sac : internal auditory meatus signal ratio was associated with a history of sudden or fluctuating hearing loss. Hearing loss correlated with opercular and extraosseous endolymphatic sac size measurements. A larger midpoint intraosseous endolymphatic sac size was associated with clear fluid loss at cochlear implantation.
The magnetic resonance imaging characteristics of large endolymphatic sac compartments have been defined. The endolymphatic sac size and distal compartment signal should be recorded, as these provide prognostic information and assist the planning of appropriate interventions.
（1）研究在薄层T2加权和T2*加权磁共振成像上大的内淋巴囊内部间隔的患病率和特征，并将这些与其他大的内淋巴囊磁共振成像特征相关联；（2）将间隔成像特征、内淋巴囊大小和迷路异常与患者的临床和听力学数据相关联。
在一家三级转诊中心对38例患有大的内淋巴囊异常的患者的磁共振成像研究进行回顾性分析。评估内淋巴囊间隔的存在、形态和成像信号。记录内淋巴囊大小和迷路异常。将内淋巴囊间隔和其他成像特征与临床和听力学数据相关联。
57%的成像内淋巴囊中存在间隔，但仅其存在与其他成像特征或临床数据无关。内淋巴囊与内耳道信号比与突发或波动性听力损失病史相关。听力损失与前庭和骨外内淋巴囊大小测量相关。较大的骨内中点内淋巴囊大小与人工耳蜗植入时的明显液体流失相关。
已明确大的内淋巴囊间隔的磁共振成像特征。应记录内淋巴囊大小和远端间隔信号，因为这些可提供预后信息并有助于规划适当的干预措施。
