PharmGKB 总结： GSTT1 非常重要的药物基因信息。
PharmGKB summary: very important pharmacogene information for GSTT1.
机构信息
Department of Genetics, Stanford University Medical Center, Stanford, California, USA.
出版信息
Pharmacogenet Genomics. 2012 Aug;22(8):646-51. doi: 10.1097/FPC.0b013e3283527c02.
Abstract
This PharmGKB summary briefly discusses the very important pharmacogene and its variants that can influence drug responses. A fully interactive version of this short review, with links to individual paper annotations and population descriptions can be found at http://www.pharmgkb.org/vip/PA183.
摘要
本 PharmGKB 摘要简要讨论了可影响药物反应的非常重要的药物基因及其变体。该短文评阅的一个完全交互式版本，其中包含到各个论文注释和人群描述的链接，可在 http://www.pharmgkb.org/vip/PA183 找到。
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2
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