Department of Otorhinolaryngology, Izzet Baysal Medicine Faculty of Abant Izzet Baysal University, Bolu, Turkey.
Am J Rhinol Allergy. 2012 May-Jun;26(3):e104-6. doi: 10.2500/ajra.2012.26.3757.
The anatomy of the nasal passages, pharynx, and larynx and evaluation of mucous membranes and laryngeal function is well observed by transnasal fiberoptic laryngoscopy (TFL). In this procedure, to provide good local infiltrative analgesia, medication such as anesthetics is important for the otolaryngologist. The aim of this study was to evaluate the efficacy of lidocaine (L) spray, compared with levobupivacaine solution, used for local anesthetic in patients undergoing TFL for complete examination.
Sixty-two subjects (39 men and 23 women; mean age, 36 ± 7 years) were enrolled in the study. Patients were randomly classified into two groups as levobupivacaine hydroclorur (LB) and L groups. A standard flexible transnasal fiberoptic 4.2-mm-diameter laryngoscope was passed through the nasal cavity and into the aerodigestive tract. Patients were asked to evaluate the intensity of the pain they experienced during the TFL, using a visual analog scale (VAS) and Ramsay sedation scale.
Demographic data were similar in both groups. There was no difference in VAS and Ramsay scores between both groups (p > 0.05).
Our findings indicated that topical levobupivacaine seems to be an effective medication for anesthesia of the nasal mucosa and may be used to allow complete examinations involving TFL.
经鼻纤维喉镜（TFL）可很好地观察鼻腔、咽和喉的解剖结构，并评估黏膜和喉功能。在该过程中，耳鼻喉科医生需要使用局部浸润麻醉药物（如麻醉剂）来提供良好的局部浸润镇痛。本研究旨在评估利多卡因（L）喷雾与左旋布比卡因溶液在 TFL 全面检查中用作局部麻醉药物的效果。
共纳入 62 名患者（39 名男性和 23 名女性；平均年龄 36 ± 7 岁），将患者随机分为两组：左布比卡因盐酸盐（LB）组和 L 组。通过鼻腔插入标准的软性经鼻纤维喉镜，进入呼吸道和消化道。患者使用视觉模拟评分（VAS）和 Ramsay 镇静评分评估在 TFL 过程中经历的疼痛强度。
两组的人口统计学数据相似。两组的 VAS 和 Ramsay 评分无差异（p＞0.05）。
我们的研究结果表明，局部应用左布比卡因似乎是一种有效的鼻黏膜麻醉药物，可用于允许进行 TFL 全面检查。
