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利多卡因喷雾与丁卡因溶液用于经鼻纤维喉镜检查。

Lidocaine spray vs tetracaine solution for transnasal fiber-optic laryngoscopy.

机构信息

Department of Otolaryngology, Naval Hospital of Crete, K. Palma 14, Chania, Crete, Greece.

出版信息

Am J Otolaryngol. 2010 Mar-Apr;31(2):114-6. doi: 10.1016/j.amjoto.2008.11.011. Epub 2009 Mar 27.

Abstract

STATEMENT OF PROBLEM

The aim of this study was to evaluate the efficacy of lidocaine spray 10%, compared with tetracaine 2% solution, as a local anesthetic for patients undergoing transnasal fiber-optic laryngoscopy.

METHOD OF STUDY

A prospective study was conducted on patients undergoing transnasal fiber-optic laryngoscopy. Microsurgical sponges were applied in each side of the nose for 10 minutes before laryngoscopy. Patients were randomly classified into group A and group B, in which tetracaine 2% solution and lidocaine spray 10% were used, respectively. Patients were asked to evaluate the severity of pain during the procedure by a visual analog scale. Patients data, pain score, and potential complications were placed in a database and statistically assessed.

MAIN RESULTS

Our series consisted of 48 patients. Statistical analysis showed significant lower mean nasal discomfort score in favor of the tetracaine group (2.29 vs 3.04 [P < .001]). No tetracaine complications or side effects occurred.

PRINCIPAL CONCLUSION

Neurosurgical sponge application of tetracaine 2% solution is an easy, safe, inexpensive, and effective analgesia for transnasal fiber-optic laryngoscopy.

摘要

问题陈述

本研究旨在评估利多卡因喷雾 10%与 2%丁卡因溶液作为经鼻纤维喉镜检查患者局部麻醉的疗效。

研究方法

对行经鼻纤维喉镜检查的患者进行前瞻性研究。在喉镜检查前,将微外科海绵应用于每侧鼻腔 10 分钟。患者随机分为 A 组和 B 组,分别使用 2%丁卡因溶液和利多卡因喷雾 10%。患者通过视觉模拟评分法评估术中疼痛的严重程度。患者数据、疼痛评分和潜在并发症被置于数据库中并进行统计学评估。

主要结果

我们的系列研究包括 48 例患者。统计分析显示,利多卡因组的平均鼻部不适评分明显较低(2.29 比 3.04[P<0.001])。未发生丁卡因相关并发症或不良反应。

主要结论

经鼻应用 2%丁卡因溶液的神经外科海绵是经鼻纤维喉镜检查的一种简便、安全、经济且有效的镇痛方法。

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