解析种间细菌通讯。
Deconvoluting interspecies bacterial communication.
机构信息
Department of Chemistry, North Carolina State University, Raleigh, NC 27695, USA.
出版信息
Angew Chem Int Ed Engl. 2012 Jun 25;51(26):6314-5. doi: 10.1002/anie.201202440. Epub 2012 May 29.
PMID:22644666
Abstract
The universal bacterial signal molecule autoinducer-2 (AI-2) is derived from 4,5-dihydroxy-2,3-pentanedione (DPD). DPD exists in a complex equilibrium between multiple forms, and NMR spectroscopy has now been used to establish that the extent of the structural diversity displayed by DPD over a broad pH range is even greater than previously posited.
摘要
普遍存在于细菌中的信号分子——自动诱导因子 2（AI-2）来源于 4,5-二羟基-2,3-戊二酮（DPD）。DPD 以多种形式存在于复杂的平衡中，如今 NMR 光谱已被用于证实，DPD 在广泛的 pH 范围内所表现出的结构多样性程度甚至比之前推测的还要大。
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