Uncharacterized 4,5-dihydroxy-2,3-pentanedione (DPD) molecules revealed through NMR spectroscopy: implications for a greater signaling diversity in bacterial species.
作者信息
Globisch Daniel, Lowery Colin A, McCague Karen C, Janda Kim D
机构信息
Department of Chemistry, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
出版信息
Angew Chem Int Ed Engl. 2012 Apr 23;51(17):4204-8. doi: 10.1002/anie.201109149. Epub 2012 Feb 29.
Abstract
摘要
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Synthetic polymers for simultaneous bacterial sequestration and quorum sense interference.用于同时细菌隔离和群体感应干扰的合成聚合物。
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Probing autoinducer-2 based quorum sensing: the biological consequences of molecules unable to traverse equilibrium states.基于群体感应的自动诱导物-2 的探测：无法穿越平衡态的分子的生物学后果。
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Synthetic analogs tailor native AI-2 signaling across bacterial species.合成类似物可调整不同细菌物种的内源性 AI-2 信号。
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Establishing a quantitative definition of quorum sensing provides insight into the information content of the autoinducer signals in Vibrio harveyi and Escherichia coli.建立群体感应的定量定义，有助于深入了解 Harvey 氏弧菌和大肠杆菌中自体诱导物信号的信息含量。
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Bacterial quorum-sensing network architectures.细菌群体感应网络架构
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Direct quantitation of the quorum sensing signal, autoinducer-2, in clinically relevant samples by liquid chromatography-tandem mass spectrometry.液相色谱-串联质谱法直接定量临床相关样本中的群体感应信号自诱导物-2。
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Inhibition of Pseudomonas aeruginosa quorum sensing by AI-2 analogs.AI-2类似物对铜绿假单胞菌群体感应的抑制作用。
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Sinorhizobium meliloti, a bacterium lacking the autoinducer-2 (AI-2) synthase, responds to AI-2 supplied by other bacteria.苜蓿中华根瘤菌是一种缺乏自诱导物-2（AI-2）合酶的细菌，它对其他细菌提供的AI-2有反应。
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