Radboud University Nijmegen Medical Centre, Nijmegen Centre for Evidence Based Practice, Department of Rehabilitation, PO Box 9101 or 818, 6500 HB Nijmegen, The Netherlands.
Muscle Nerve. 2012 Jul;46(1):31-7. doi: 10.1002/mus.23277. Epub 2012 May 29.
The purpose of this study was to assess the feasibility of quantitative muscle ultrasound (QMUS) to visualize oral muscles and to establish normative data for muscle thickness and echo intensity of submental and tongue muscles in healthy children and young adults. The data were compared with those of 5 patients with Duchenne muscular dystrophy (DMD).
Ultrasound images from the suprahyoid region and from the surface of the tongue were made in 53 healthy subjects aged 5 to 30 years.
All measurements were feasible in all subjects and patients with good reproducibility except for the mylohyoid muscle. Muscle thickness depended on height, and echo intensity depended on weight. Our findings suggest gradual involvement of oral muscles in DMD.
QMUS in oral muscles is feasible in healthy children, adults and patients with DMD. These data show that it is possible to differentiate between healthy persons and patients with DMD.
本研究旨在评估定量肌肉超声(QMUS)可视化口腔肌肉的可行性,并为健康儿童和年轻成年人颏下和舌肌的肌肉厚度和回声强度建立正常数据。将这些数据与 5 名杜氏肌营养不良症(DMD)患者的数据进行了比较。
对 53 名年龄在 5 至 30 岁的健康受试者的颏下区域和舌面进行了超声图像检查。
除下颌舌骨肌外,所有测量在所有受试者和患者中均具有良好的可重复性。肌肉厚度取决于身高,回声强度取决于体重。我们的研究结果表明,DMD 患者的口腔肌肉逐渐受累。
QMUS 在健康儿童、成人和 DMD 患者的口腔肌肉中是可行的。这些数据表明,QMUS 有可能区分健康人和 DMD 患者。